4HFM
X-ray Crystal Structure of a NADP(H)-bound Double Bond Reductase from Nicotiana tabacum
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0016628 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor |
A | 0032440 | molecular_function | 2-alkenal reductase [NAD(P)+] activity |
A | 0035798 | molecular_function | 2-alkenal reductase (NADPH) activity |
B | 0016491 | molecular_function | oxidoreductase activity |
B | 0016628 | molecular_function | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor |
B | 0032440 | molecular_function | 2-alkenal reductase [NAD(P)+] activity |
B | 0035798 | molecular_function | 2-alkenal reductase (NADPH) activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 35 |
Details | BINDING SITE FOR RESIDUE NAP A 400 |
Chain | Residue |
A | PRO54 |
A | TYR206 |
A | GLN210 |
A | ASN230 |
A | VAL231 |
A | CYS252 |
A | GLY253 |
A | ILE255 |
A | SER256 |
A | TYR258 |
A | PHE282 |
A | MET136 |
A | LEU283 |
A | VAL284 |
A | LEU327 |
A | PHE328 |
A | GLY330 |
A | ASN332 |
A | HOH501 |
A | HOH502 |
A | HOH504 |
A | HOH509 |
A | THR140 |
A | HOH511 |
A | HOH516 |
A | HOH570 |
A | HOH616 |
A | HOH630 |
A | HOH668 |
A | GLY164 |
A | ALA165 |
A | VAL166 |
A | ALA185 |
A | GLY186 |
A | LYS190 |
site_id | AC2 |
Number of Residues | 25 |
Details | BINDING SITE FOR RESIDUE NAP B 400 |
Chain | Residue |
B | PRO54 |
B | MET136 |
B | THR140 |
B | ALA161 |
B | GLY164 |
B | ALA165 |
B | VAL166 |
B | ALA185 |
B | GLY186 |
B | LYS190 |
B | TYR206 |
B | ASN230 |
B | CYS252 |
B | GLY253 |
B | ILE255 |
B | PHE282 |
B | LEU283 |
B | VAL284 |
B | GLY330 |
B | ASN332 |
B | LYS335 |
B | HOH506 |
B | HOH513 |
B | HOH540 |
B | HOH585 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000250 |
Chain | Residue | Details |
A | TYR55 | |
A | TYR80 | |
B | TYR55 | |
B | TYR80 |
site_id | SWS_FT_FI2 |
Number of Residues | 18 |
Details | BINDING: BINDING => ECO:0000269|DOI:10.1021/cs300709m |
Chain | Residue | Details |
A | ALA165 | |
B | ALA165 | |
B | GLY186 | |
B | LYS190 | |
B | TYR206 | |
B | ASN230 | |
B | CYS252 | |
B | TYR258 | |
B | PHE282 | |
B | ASN332 | |
A | GLY186 | |
A | LYS190 | |
A | TYR206 | |
A | ASN230 | |
A | CYS252 | |
A | TYR258 | |
A | PHE282 | |
A | ASN332 |