4H8I

Structure of GluK2-LBD in complex with GluAzo

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0015276	molecular_function	ligand-gated monoatomic ion channel activity
A	0016020	cellular_component	membrane
B	0015276	molecular_function	ligand-gated monoatomic ion channel activity
B	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE 11W A 301

Chain	Residue
A	ASP58
A	ALA142
A	THR143
A	LYS172
A	GLU191
A	HOH446
A	HOH469
A	HOH496
A	HOH566
B	SER5
B	GLU52
A	GLY59
A	TYR61
A	PRO89
A	LEU90
A	ALA91
A	ARG96
A	VAL138
A	GLY141

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 302

Chain	Residue
A	LYS104
A	HOH458
B	LYS104
B	HOH481

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 303

Chain	Residue
A	ARG31
A	LEU55
A	HOH473
B	GLU57
B	HOH487
B	HOH511

---

site_id	AC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE MES B 301

Chain	Residue
B	GLU13
B	TYR61
B	PRO89
B	ALA91
B	ARG96
B	GLU191
B	TYR217
B	HOH509
B	HOH541
B	HOH587

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15721240","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17115050","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"38778115","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"39592599","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1S50","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1S7Y","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2I0B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2I0C","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B36","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B37","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B38","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9B39","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9DXQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9DXR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9DXS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"9DXT","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"15677325","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8163463","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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