4GZ2
Mus Musculus Tdp2 excluded ssDNA complex
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FMT A 401 |
| Chain | Residue |
| A | GLN304 |
| A | ARG324 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 402 |
| Chain | Residue |
| A | ASP132 |
| A | GLU162 |
| A | HOH556 |
| A | HOH557 |
| A | HOH603 |
| D | DT3 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG D 101 |
| Chain | Residue |
| A | HOH613 |
| C | HOH231 |
| D | HOH210 |
| D | HOH219 |
| D | HOH220 |
| A | HOH612 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT B 401 |
| Chain | Residue |
| B | ASP156 |
| B | ARG198 |
| B | HOH651 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 402 |
| Chain | Residue |
| B | ASP132 |
| B | GLU162 |
| B | HOH577 |
| B | HOH587 |
| B | HOH628 |
| C | DT3 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG C 101 |
| Chain | Residue |
| C | HOH207 |
| C | HOH208 |
| C | HOH211 |
| C | HOH218 |
| C | HOH230 |
| D | HOH218 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000305|PubMed:23104055, ECO:0000305|PubMed:27060144 |
| Chain | Residue | Details |
| A | ASP272 | |
| B | ASP272 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23104055, ECO:0000269|PubMed:27099339, ECO:0007744|PDB:4GYZ, ECO:0007744|PDB:4GZ2, ECO:0007744|PDB:5J42 |
| Chain | Residue | Details |
| A | ASP132 | |
| B | ASP132 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23104055, ECO:0000269|PubMed:24808172, ECO:0000269|PubMed:27099339, ECO:0007744|PDB:4GYZ, ECO:0007744|PDB:4GZ1, ECO:0007744|PDB:4GZ2, ECO:0007744|PDB:4PUQ, ECO:0007744|PDB:5HT2, ECO:0007744|PDB:5INP, ECO:0007744|PDB:5J42 |
| Chain | Residue | Details |
| A | GLU162 | |
| B | GLU162 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | SITE: Interaction with 5' end of substrate DNA => ECO:0000269|PubMed:23104055, ECO:0000269|PubMed:27060144 |
| Chain | Residue | Details |
| A | TYR188 | |
| B | TYR188 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | SITE: Interaction with 5' end of substrate DNA => ECO:0000269|PubMed:23104055, ECO:0000269|PubMed:24808172, ECO:0000269|PubMed:27060144 |
| Chain | Residue | Details |
| A | TRP307 | |
| A | HIS359 | |
| B | TRP307 | |
| B | HIS359 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | SITE: Interaction with 5' end of substrate DNA => ECO:0000269|PubMed:23104055 |
| Chain | Residue | Details |
| A | PHE325 | |
| B | PHE325 |
