4GZ2

Mus Musculus Tdp2 excluded ssDNA complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
B	0003824	molecular_function	catalytic activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE FMT A 401

Chain	Residue
A	GLN304
A	ARG324

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 402

Chain	Residue
A	ASP132
A	GLU162
A	HOH556
A	HOH557
A	HOH603
D	DT3

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG D 101

Chain	Residue
A	HOH613
C	HOH231
D	HOH210
D	HOH219
D	HOH220
A	HOH612

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FMT B 401

Chain	Residue
B	ASP156
B	ARG198
B	HOH651

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B 402

Chain	Residue
B	ASP132
B	GLU162
B	HOH577
B	HOH587
B	HOH628
C	DT3

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG C 101

Chain	Residue
C	HOH207
C	HOH208
C	HOH211
C	HOH218
C	HOH230
D	HOH218

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Region: {"description":"Interaction with 5' end of substrate DNA","evidences":[{"source":"PubMed","id":"23104055","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27060144","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	26
Details	Region: {"description":"Interaction with 5' end of substrate DNA","evidences":[{"source":"PubMed","id":"23104055","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24808172","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27060144","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"23104055","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"27060144","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23104055","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27099339","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4GYZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4GZ2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5J42","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"23104055","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24808172","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27099339","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4GYZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4GZ1","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4GZ2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4PUQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5HT2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5INP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5J42","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	Site: {"description":"Interaction with 5' end of substrate DNA","evidences":[{"source":"PubMed","id":"23104055","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27060144","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	Site: {"description":"Interaction with 5' end of substrate DNA","evidences":[{"source":"PubMed","id":"23104055","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"24808172","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"27060144","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	2
Details	Site: {"description":"Interaction with 5' end of substrate DNA","evidences":[{"source":"PubMed","id":"23104055","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---