Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004616 | molecular_function | phosphogluconate dehydrogenase (decarboxylating) activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006098 | biological_process | pentose-phosphate shunt |
| A | 0009051 | biological_process | pentose-phosphate shunt, oxidative branch |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019322 | biological_process | pentose biosynthetic process |
| A | 0019521 | biological_process | D-gluconate metabolic process |
| A | 0046177 | biological_process | D-gluconate catabolic process |
| A | 0050661 | molecular_function | NADP binding |
| A | 0070062 | cellular_component | extracellular exosome |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE MES A 501 |
| Chain | Residue |
| A | GLU104 |
| A | TYR105 |
| A | ARG106 |
| A | MET184 |
| A | TRP265 |
| A | HOH617 |
| A | HOH646 |
| A | HOH813 |
| A | HOH1033 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MES A 502 |
| Chain | Residue |
| A | GLY130 |
| A | GLU131 |
| A | GLY166 |
| A | GLY450 |
| A | ALA451 |
| A | HOH1079 |
Functional Information from PROSITE/UniProt
| site_id | PS00461 |
| Number of Residues | 13 |
| Details | 6PGD 6-phosphogluconate dehydrogenase signature. IrDsaGQKGTGkW |
| Chain | Residue | Details |
| A | ILE253-TRP265 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton acceptor => ECO:0000250 |
| Chain | Residue | Details |
| A | LYS183 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor => ECO:0000250 |
| Chain | Residue | Details |
| A | GLU190 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | BINDING: in other chain => ECO:0000269|Ref.9 |
| Chain | Residue | Details |
| A | GLY9 | |
| A | ASN32 | |
| A | VAL74 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | BINDING: in other chain => ECO:0000250 |
| Chain | Residue | Details |
| A | ASN102 | |
| A | SER128 | |
| A | HIS186 | |
| A | TYR191 | |
| A | LYS260 | |
| A | ARG287 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | ARG446 | |
| A | HIS452 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|Ref.9 |
| Chain | Residue | Details |
| A | SER477 | |
| Chain | Residue | Details |
| A | LYS37 | |
| Chain | Residue | Details |
| A | SER56 | |
| A | SER128 | |
| Chain | Residue | Details |
| A | LYS58 | |
| A | LYS308 | |
