Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004222 | molecular_function | metalloendopeptidase activity |
A | 0006508 | biological_process | proteolysis |
A | 0008237 | molecular_function | metallopeptidase activity |
A | 0008270 | molecular_function | zinc ion binding |
A | 0031012 | cellular_component | extracellular matrix |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN A 301 |
Chain | Residue |
A | HIS218 |
A | HIS222 |
A | HIS228 |
A | KLJ306 |
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE ZN A 302 |
Chain | Residue |
A | HIS168 |
A | ASP170 |
A | HIS183 |
A | HIS196 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE CA A 303 |
Chain | Residue |
A | GLY190 |
A | GLY192 |
A | ASP194 |
A | HOH433 |
A | ASP158 |
site_id | AC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE CA A 304 |
Chain | Residue |
A | ASP124 |
A | GLU199 |
A | GLU201 |
A | HOH412 |
site_id | AC5 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE CA A 305 |
Chain | Residue |
A | ASP175 |
A | GLY176 |
A | GLY178 |
A | ILE180 |
A | ASP198 |
A | GLU201 |
site_id | AC6 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE KLJ A 306 |
Chain | Residue |
A | GLY179 |
A | LEU181 |
A | ALA182 |
A | HIS218 |
A | GLU219 |
A | HIS222 |
A | HIS228 |
A | VAL235 |
A | PHE237 |
A | PRO238 |
A | THR239 |
A | ZN301 |
A | HOH475 |
Functional Information from PROSITE/UniProt
site_id | PS00142 |
Number of Residues | 10 |
Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TAVHEIGHSL |
Chain | Residue | Details |
A | THR215-LEU224 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: |
Chain | Residue | Details |
A | GLU219 | |
site_id | SWS_FT_FI2 |
Number of Residues | 19 |
Details | BINDING: |
Chain | Residue | Details |
A | ASP124 | |
A | GLY190 | |
A | GLY192 | |
A | ASP194 | |
A | HIS196 | |
A | ASP198 | |
A | GLU199 | |
A | GLU201 | |
A | HIS218 | |
A | HIS222 | |
A | HIS228 | |
A | ASP158 | |
A | HIS168 | |
A | ASP170 | |
A | ASP175 | |
A | GLY176 | |
A | GLY178 | |
A | ILE180 | |
A | HIS183 | |