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4GTU

LIGAND-FREE HOMODIMERIC HUMAN GLUTATHIONE S-TRANSFERASE M4-4

Functional Information from GO Data
ChainGOidnamespacecontents
A0004364molecular_functionglutathione transferase activity
A0004464molecular_functionleukotriene-C4 synthase activity
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006629biological_processlipid metabolic process
A0006749biological_processglutathione metabolic process
A0016740molecular_functiontransferase activity
A0016829molecular_functionlyase activity
A0018916biological_processnitrobenzene metabolic process
A0019899molecular_functionenzyme binding
A0042178biological_processxenobiotic catabolic process
A0042759biological_processlong-chain fatty acid biosynthetic process
A0042802molecular_functionidentical protein binding
A0042803molecular_functionprotein homodimerization activity
A0043295molecular_functionglutathione binding
B0004364molecular_functionglutathione transferase activity
B0004464molecular_functionleukotriene-C4 synthase activity
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006629biological_processlipid metabolic process
B0006749biological_processglutathione metabolic process
B0016740molecular_functiontransferase activity
B0016829molecular_functionlyase activity
B0018916biological_processnitrobenzene metabolic process
B0019899molecular_functionenzyme binding
B0042178biological_processxenobiotic catabolic process
B0042759biological_processlong-chain fatty acid biosynthetic process
B0042802molecular_functionidentical protein binding
B0042803molecular_functionprotein homodimerization activity
B0043295molecular_functionglutathione binding
C0004364molecular_functionglutathione transferase activity
C0004464molecular_functionleukotriene-C4 synthase activity
C0005515molecular_functionprotein binding
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0006629biological_processlipid metabolic process
C0006749biological_processglutathione metabolic process
C0016740molecular_functiontransferase activity
C0016829molecular_functionlyase activity
C0018916biological_processnitrobenzene metabolic process
C0019899molecular_functionenzyme binding
C0042178biological_processxenobiotic catabolic process
C0042759biological_processlong-chain fatty acid biosynthetic process
C0042802molecular_functionidentical protein binding
C0042803molecular_functionprotein homodimerization activity
C0043295molecular_functionglutathione binding
D0004364molecular_functionglutathione transferase activity
D0004464molecular_functionleukotriene-C4 synthase activity
D0005515molecular_functionprotein binding
D0005737cellular_componentcytoplasm
D0005829cellular_componentcytosol
D0006629biological_processlipid metabolic process
D0006749biological_processglutathione metabolic process
D0016740molecular_functiontransferase activity
D0016829molecular_functionlyase activity
D0018916biological_processnitrobenzene metabolic process
D0019899molecular_functionenzyme binding
D0042178biological_processxenobiotic catabolic process
D0042759biological_processlong-chain fatty acid biosynthetic process
D0042802molecular_functionidentical protein binding
D0042803molecular_functionprotein homodimerization activity
D0043295molecular_functionglutathione binding
E0004364molecular_functionglutathione transferase activity
E0004464molecular_functionleukotriene-C4 synthase activity
E0005515molecular_functionprotein binding
E0005737cellular_componentcytoplasm
E0005829cellular_componentcytosol
E0006629biological_processlipid metabolic process
E0006749biological_processglutathione metabolic process
E0016740molecular_functiontransferase activity
E0016829molecular_functionlyase activity
E0018916biological_processnitrobenzene metabolic process
E0019899molecular_functionenzyme binding
E0042178biological_processxenobiotic catabolic process
E0042759biological_processlong-chain fatty acid biosynthetic process
E0042802molecular_functionidentical protein binding
E0042803molecular_functionprotein homodimerization activity
E0043295molecular_functionglutathione binding
F0004364molecular_functionglutathione transferase activity
F0004464molecular_functionleukotriene-C4 synthase activity
F0005515molecular_functionprotein binding
F0005737cellular_componentcytoplasm
F0005829cellular_componentcytosol
F0006629biological_processlipid metabolic process
F0006749biological_processglutathione metabolic process
F0016740molecular_functiontransferase activity
F0016829molecular_functionlyase activity
F0018916biological_processnitrobenzene metabolic process
F0019899molecular_functionenzyme binding
F0042178biological_processxenobiotic catabolic process
F0042759biological_processlong-chain fatty acid biosynthetic process
F0042802molecular_functionidentical protein binding
F0042803molecular_functionprotein homodimerization activity
F0043295molecular_functionglutathione binding
G0004364molecular_functionglutathione transferase activity
G0004464molecular_functionleukotriene-C4 synthase activity
G0005515molecular_functionprotein binding
G0005737cellular_componentcytoplasm
G0005829cellular_componentcytosol
G0006629biological_processlipid metabolic process
G0006749biological_processglutathione metabolic process
G0016740molecular_functiontransferase activity
G0016829molecular_functionlyase activity
G0018916biological_processnitrobenzene metabolic process
G0019899molecular_functionenzyme binding
G0042178biological_processxenobiotic catabolic process
G0042759biological_processlong-chain fatty acid biosynthetic process
G0042802molecular_functionidentical protein binding
G0042803molecular_functionprotein homodimerization activity
G0043295molecular_functionglutathione binding
H0004364molecular_functionglutathione transferase activity
H0004464molecular_functionleukotriene-C4 synthase activity
H0005515molecular_functionprotein binding
H0005737cellular_componentcytoplasm
H0005829cellular_componentcytosol
H0006629biological_processlipid metabolic process
H0006749biological_processglutathione metabolic process
H0016740molecular_functiontransferase activity
H0016829molecular_functionlyase activity
H0018916biological_processnitrobenzene metabolic process
H0019899molecular_functionenzyme binding
H0042178biological_processxenobiotic catabolic process
H0042759biological_processlong-chain fatty acid biosynthetic process
H0042802molecular_functionidentical protein binding
H0042803molecular_functionprotein homodimerization activity
H0043295molecular_functionglutathione binding
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues688
DetailsDomain: {"description":"GST N-terminal"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues944
DetailsDomain: {"description":"GST C-terminal"}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues56
DetailsBinding site: {"evidences":[{"source":"UniProtKB","id":"P08515","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues8
DetailsBinding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

Catalytic Information from CSA
site_idCSA1
Number of Residues1
DetailsAnnotated By Reference To The Literature 1oe8
ChainResidueDetails
ATYR6

site_idCSA2
Number of Residues1
DetailsAnnotated By Reference To The Literature 1oe8
ChainResidueDetails
BTYR6

site_idCSA3
Number of Residues1
DetailsAnnotated By Reference To The Literature 1oe8
ChainResidueDetails
CTYR6

site_idCSA4
Number of Residues1
DetailsAnnotated By Reference To The Literature 1oe8
ChainResidueDetails
DTYR6

site_idCSA5
Number of Residues1
DetailsAnnotated By Reference To The Literature 1oe8
ChainResidueDetails
ETYR6

site_idCSA6
Number of Residues1
DetailsAnnotated By Reference To The Literature 1oe8
ChainResidueDetails
FTYR6

site_idCSA7
Number of Residues1
DetailsAnnotated By Reference To The Literature 1oe8
ChainResidueDetails
GTYR6

site_idCSA8
Number of Residues1
DetailsAnnotated By Reference To The Literature 1oe8
ChainResidueDetails
HTYR6

242842

PDB entries from 2025-10-08

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