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4GSK

Crystal structure of an Atg7-Atg10 crosslinked complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0000407cellular_componentphagophore assembly site
A0000422biological_processautophagy of mitochondrion
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005829cellular_componentcytosol
A0006914biological_processautophagy
A0006995biological_processcellular response to nitrogen starvation
A0008270molecular_functionzinc ion binding
A0008641molecular_functionubiquitin-like modifier activating enzyme activity
A0015031biological_processprotein transport
A0016020cellular_componentmembrane
A0016236biological_processmacroautophagy
A0019778molecular_functionAtg12 activating enzyme activity
A0019779molecular_functionAtg8 activating enzyme activity
A0032258biological_processcytoplasm to vacuole targeting by the Cvt pathway
A0032446biological_processprotein modification by small protein conjugation
A0034727biological_processpiecemeal microautophagy of the nucleus
A0042802molecular_functionidentical protein binding
A0044804biological_processnucleophagy
A0097632cellular_componentextrinsic component of phagophore assembly site membrane
B0000407cellular_componentphagophore assembly site
B0000422biological_processautophagy of mitochondrion
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0005829cellular_componentcytosol
B0006914biological_processautophagy
B0006995biological_processcellular response to nitrogen starvation
B0008270molecular_functionzinc ion binding
B0008641molecular_functionubiquitin-like modifier activating enzyme activity
B0015031biological_processprotein transport
B0016020cellular_componentmembrane
B0016236biological_processmacroautophagy
B0019778molecular_functionAtg12 activating enzyme activity
B0019779molecular_functionAtg8 activating enzyme activity
B0032258biological_processcytoplasm to vacuole targeting by the Cvt pathway
B0032446biological_processprotein modification by small protein conjugation
B0034727biological_processpiecemeal microautophagy of the nucleus
B0042802molecular_functionidentical protein binding
B0044804biological_processnucleophagy
B0097632cellular_componentextrinsic component of phagophore assembly site membrane
Y0000422biological_processautophagy of mitochondrion
Y0005515molecular_functionprotein binding
Y0005575cellular_componentcellular_component
Y0006914biological_processautophagy
Y0015031biological_processprotein transport
Y0016020cellular_componentmembrane
Y0016236biological_processmacroautophagy
Y0016740molecular_functiontransferase activity
Y0019777molecular_functionAtg12 transferase activity
Y0019787molecular_functionubiquitin-like protein transferase activity
Y0032258biological_processcytoplasm to vacuole targeting by the Cvt pathway
Y0032446biological_processprotein modification by small protein conjugation
Y0034045cellular_componentphagophore assembly site membrane
Y0034727biological_processpiecemeal microautophagy of the nucleus
Y0044804biological_processnucleophagy
Z0000422biological_processautophagy of mitochondrion
Z0005515molecular_functionprotein binding
Z0005575cellular_componentcellular_component
Z0006914biological_processautophagy
Z0015031biological_processprotein transport
Z0016020cellular_componentmembrane
Z0016236biological_processmacroautophagy
Z0016740molecular_functiontransferase activity
Z0019777molecular_functionAtg12 transferase activity
Z0019787molecular_functionubiquitin-like protein transferase activity
Z0032258biological_processcytoplasm to vacuole targeting by the Cvt pathway
Z0032446biological_processprotein modification by small protein conjugation
Z0034045cellular_componentphagophore assembly site membrane
Z0034727biological_processpiecemeal microautophagy of the nucleus
Z0044804biological_processnucleophagy
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A 701
ChainResidue
ACYS485
ACYS488
ACYS569
ACYS572

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN B 701
ChainResidue
BCYS485
BCYS488
BCYS569
BCYS572

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: Glycyl thioester intermediate
ChainResidueDetails
YCYS133
ZCYS133

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PDB entries from 2024-11-06

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