4GMH

Crystal structure of staphylococcus aureus 5'-methylthioadenosine/s-adenosylhomocysteine nucleosidase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0005829	cellular_component	cytosol
A	0008782	molecular_function	adenosylhomocysteine nucleosidase activity
A	0008930	molecular_function	methylthioadenosine nucleosidase activity
A	0009086	biological_process	methionine biosynthetic process
A	0009116	biological_process	nucleoside metabolic process
A	0009164	biological_process	nucleoside catabolic process
A	0016787	molecular_function	hydrolase activity
A	0019284	biological_process	L-methionine salvage from S-adenosylmethionine
A	0019509	biological_process	L-methionine salvage from methylthioadenosine

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACT A 301

Chain	Residue
A	GLY-1
A	ASN17
A	LEU228

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACT A 302

Chain	Residue
A	PHE150
A	ILE151
A	VAL170
A	ASP196
A	HOH449

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACT A 303

Chain	Residue
A	GLU171
A	MET172
A	GLU173
A	HOH535
A	SER75

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000255|HAMAP-Rule:MF_01684

Chain	Residue	Details
A	GLU11

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_01684

Chain	Residue	Details
A	ASP196

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01684

Chain	Residue	Details
A	GLY77
A	ILE151
A	MET172

---