4GLV
OBody AM3L09 bound to hen egg-white lysozyme
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003796 | molecular_function | lysozyme activity |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005783 | cellular_component | endoplasmic reticulum |
| A | 0016231 | molecular_function | beta-N-acetylglucosaminidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0016998 | biological_process | cell wall macromolecule catabolic process |
| A | 0031640 | biological_process | killing of cells of another organism |
| A | 0042742 | biological_process | defense response to bacterium |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0050829 | biological_process | defense response to Gram-negative bacterium |
| A | 0050830 | biological_process | defense response to Gram-positive bacterium |
| A | 0051672 | biological_process | obsolete catabolism by organism of cell wall peptidoglycan in other organism |
| B | 0003676 | molecular_function | nucleic acid binding |
| C | 0003796 | molecular_function | lysozyme activity |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005576 | cellular_component | extracellular region |
| C | 0005615 | cellular_component | extracellular space |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005783 | cellular_component | endoplasmic reticulum |
| C | 0016231 | molecular_function | beta-N-acetylglucosaminidase activity |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| C | 0016998 | biological_process | cell wall macromolecule catabolic process |
| C | 0031640 | biological_process | killing of cells of another organism |
| C | 0042742 | biological_process | defense response to bacterium |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0050829 | biological_process | defense response to Gram-negative bacterium |
| C | 0050830 | biological_process | defense response to Gram-positive bacterium |
| C | 0051672 | biological_process | obsolete catabolism by organism of cell wall peptidoglycan in other organism |
| D | 0003676 | molecular_function | nucleic acid binding |
| E | 0003796 | molecular_function | lysozyme activity |
| E | 0003824 | molecular_function | catalytic activity |
| E | 0005515 | molecular_function | protein binding |
| E | 0005576 | cellular_component | extracellular region |
| E | 0005615 | cellular_component | extracellular space |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005783 | cellular_component | endoplasmic reticulum |
| E | 0016231 | molecular_function | beta-N-acetylglucosaminidase activity |
| E | 0016787 | molecular_function | hydrolase activity |
| E | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| E | 0016998 | biological_process | cell wall macromolecule catabolic process |
| E | 0031640 | biological_process | killing of cells of another organism |
| E | 0042742 | biological_process | defense response to bacterium |
| E | 0042802 | molecular_function | identical protein binding |
| E | 0050829 | biological_process | defense response to Gram-negative bacterium |
| E | 0050830 | biological_process | defense response to Gram-positive bacterium |
| E | 0051672 | biological_process | obsolete catabolism by organism of cell wall peptidoglycan in other organism |
| F | 0003676 | molecular_function | nucleic acid binding |
| G | 0003796 | molecular_function | lysozyme activity |
| G | 0003824 | molecular_function | catalytic activity |
| G | 0005515 | molecular_function | protein binding |
| G | 0005576 | cellular_component | extracellular region |
| G | 0005615 | cellular_component | extracellular space |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0005783 | cellular_component | endoplasmic reticulum |
| G | 0016231 | molecular_function | beta-N-acetylglucosaminidase activity |
| G | 0016787 | molecular_function | hydrolase activity |
| G | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| G | 0016998 | biological_process | cell wall macromolecule catabolic process |
| G | 0031640 | biological_process | killing of cells of another organism |
| G | 0042742 | biological_process | defense response to bacterium |
| G | 0042802 | molecular_function | identical protein binding |
| G | 0050829 | biological_process | defense response to Gram-negative bacterium |
| G | 0050830 | biological_process | defense response to Gram-positive bacterium |
| G | 0051672 | biological_process | obsolete catabolism by organism of cell wall peptidoglycan in other organism |
| H | 0003676 | molecular_function | nucleic acid binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 A 201 |
| Chain | Residue |
| A | GLY4 |
| A | ARG5 |
| A | CYS6 |
| A | GLU7 |
| G | ARG14 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 A 202 |
| Chain | Residue |
| A | ILE88 |
| A | ALA11 |
| A | ARG14 |
| A | HIS15 |
| A | ASP87 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 203 |
| Chain | Residue |
| A | ASP48 |
| A | ARG61 |
| A | HOH330 |
| B | LYS37 |
| B | PHE64 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL B 201 |
| Chain | Residue |
| B | HOH303 |
| B | HOH323 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 202 |
| Chain | Residue |
| B | ARG44 |
| B | HOH307 |
| G | GLU35 |
| G | ASN44 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL C 201 |
| Chain | Residue |
| C | ARG21 |
| C | GLY22 |
| C | TYR23 |
| C | HOH325 |
| D | TRP90 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL C 202 |
| Chain | Residue |
| C | PHE34 |
| F | ASP43 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL C 203 |
| Chain | Residue |
| C | SER36 |
| C | ASN39 |
| C | ASN44 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL C 204 |
| Chain | Residue |
| C | ARG21 |
| C | ASN93 |
| C | LYS97 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL C 205 |
| Chain | Residue |
| C | PHE3 |
| C | ARG14 |
| C | HIS15 |
| C | SER86 |
| C | ASP87 |
| C | ILE88 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EPE C 206 |
| Chain | Residue |
| C | ASN19 |
| C | TYR20 |
| C | ARG21 |
| C | GLY22 |
| D | ARG89 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL D 201 |
| Chain | Residue |
| D | SER42 |
| D | GLU45 |
| D | GLY46 |
| D | GLY47 |
| E | ASN113 |
| F | GLU55 |
| F | ARG56 |
| site_id | BC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL E 201 |
| Chain | Residue |
| E | ALA122 |
| E | TRP123 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL E 202 |
| Chain | Residue |
| E | TYR20 |
| E | ARG21 |
| E | HOH338 |
| F | PO4201 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 E 203 |
| Chain | Residue |
| E | ARG14 |
| E | HIS15 |
| E | ASP87 |
| E | ILE88 |
| E | HOH337 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 F 201 |
| Chain | Residue |
| D | HIS62 |
| E | ARG21 |
| E | GOL202 |
| F | ARG89 |
| F | TRP90 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL F 202 |
| Chain | Residue |
| F | TRP26 |
| F | GLU45 |
| F | GLU73 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL F 203 |
| Chain | Residue |
| F | LYS58 |
| F | PRO60 |
| F | PHE97 |
| F | PRO98 |
| F | SER99 |
| site_id | CC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL F 204 |
| Chain | Residue |
| F | SER71 |
| F | ARG72 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL F 205 |
| Chain | Residue |
| F | ILE103 |
| F | LEU104 |
| F | ASN105 |
| F | LYS106 |
| H | ILE103 |
| site_id | CC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL F 206 |
| Chain | Residue |
| A | ASN65 |
| A | PRO79 |
| F | THR85 |
| F | THR86 |
| F | HOH333 |
| site_id | CC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PO4 G 201 |
| Chain | Residue |
| B | HIS62 |
| G | ARG21 |
| H | ARG89 |
| H | TRP90 |
| site_id | CC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL G 202 |
| Chain | Residue |
| G | TRP123 |
| site_id | CC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 H 201 |
| Chain | Residue |
| C | ASN65 |
| G | LYS116 |
| G | GLY117 |
| H | THR86 |
| H | HOH333 |
| site_id | CC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL H 202 |
| Chain | Residue |
| H | TRP8 |
| H | GLU11 |
| H | LYS5 |
| site_id | CC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL H 203 |
| Chain | Residue |
| B | ASP61 |
| H | THR88 |
| H | ARG89 |
| site_id | CC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL H 204 |
| Chain | Residue |
| A | ARG114 |
| H | GLU45 |
Functional Information from PROSITE/UniProt
| site_id | PS00128 |
| Number of Residues | 19 |
| Details | GLYCOSYL_HYDROL_F22_1 Glycosyl hydrolases family 22 (GH22) domain signature. CnipCsaLlssDItasvnC |
| Chain | Residue | Details |
| A | CYS76-CYS94 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 512 |
| Details | Domain: {"description":"C-type lysozyme","evidences":[{"source":"PROSITE-ProRule","id":"PRU00680","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Active site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 6 |
| Details | M-CSA 203 |
| Chain | Residue | Details |
| A | GLU35 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| A | ASN46 | |
| A | ASP48 | |
| A | SER50 | |
| A | ASP52 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction |
| A | ASN59 |
| site_id | MCSA2 |
| Number of Residues | 6 |
| Details | M-CSA 203 |
| Chain | Residue | Details |
| C | GLU35 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| C | ASN46 | |
| C | ASP48 | |
| C | SER50 | |
| C | ASP52 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction |
| C | ASN59 |
| site_id | MCSA3 |
| Number of Residues | 6 |
| Details | M-CSA 203 |
| Chain | Residue | Details |
| E | GLU35 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| E | ASN46 | |
| E | ASP48 | |
| E | SER50 | |
| E | ASP52 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction |
| E | ASN59 |
| site_id | MCSA4 |
| Number of Residues | 6 |
| Details | M-CSA 203 |
| Chain | Residue | Details |
| G | GLU35 | hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
| G | ASN46 | |
| G | ASP48 | |
| G | SER50 | |
| G | ASP52 | covalently attached, electrostatic stabiliser, nucleofuge, nucleophile, polar/non-polar interaction |
| G | ASN59 |
