4GDF

A Crystal Structure of SV40 Large T Antigen

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0003688	molecular_function	DNA replication origin binding
A	0005524	molecular_function	ATP binding
A	0006260	biological_process	DNA replication
B	0003677	molecular_function	DNA binding
B	0003688	molecular_function	DNA replication origin binding
B	0005524	molecular_function	ATP binding
B	0006260	biological_process	DNA replication
E	0003677	molecular_function	DNA binding
E	0003688	molecular_function	DNA replication origin binding
E	0005524	molecular_function	ATP binding
E	0006260	biological_process	DNA replication
F	0003677	molecular_function	DNA binding
F	0003688	molecular_function	DNA replication origin binding
F	0005524	molecular_function	ATP binding
F	0006260	biological_process	DNA replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 700

Chain	Residue
A	CYS302
A	CYS305
A	HIS313
A	HIS317

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 700

Chain	Residue
B	CYS302
B	CYS305
B	HIS313
B	HIS317

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN E 700

Chain	Residue
E	CYS305
E	HIS313
E	HIS317
E	CYS302

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN F 700

Chain	Residue
F	CYS302
F	CYS305
F	HIS313
F	HIS317

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	460
Details	DNA_BIND: T-ag OBD => ECO:0000255|PROSITE-ProRule:PRU00620

Chain	Residue	Details
A	PRO139-GLU254
B	PRO139-GLU254
E	PRO139-GLU254
F	PRO139-GLU254

---

site_id	SWS_FT_FI2
Number of Residues	368
Details	ZN_FING: T-ag D1-type => ECO:0000255|PROSITE-ProRule:PRU00671

Chain	Residue	Details
A	THR265-ARG357
B	THR265-ARG357
E	THR265-ARG357
F	THR265-ARG357

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00671

Chain	Residue	Details
A	CYS302
E	CYS305
E	HIS313
E	HIS317
F	CYS302
F	CYS305
F	HIS313
F	HIS317
A	CYS305
A	HIS313
A	HIS317
B	CYS302
B	CYS305
B	HIS313
B	HIS317
E	CYS302

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00551

Chain	Residue	Details
A	GLY426
B	GLY426
E	GLY426
F	GLY426

---