Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016702 | molecular_function | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
| A | 0034440 | biological_process | lipid oxidation |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FE2 A 701 |
| Chain | Residue |
| A | HIS377 |
| A | HIS382 |
| A | HIS555 |
| A | ASN559 |
| A | ILE685 |
| A | HOH801 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ZPE A 702 |
| Chain | Residue |
| A | ILE113 |
| A | LEU182 |
| A | VAL185 |
| A | ASP190 |
| A | GLU373 |
| A | HIS377 |
| A | HIS382 |
| A | PHE415 |
| A | ILE416 |
| A | GLY419 |
| A | ALA420 |
| A | ASN607 |
| A | TYR609 |
| A | ILE685 |
| A | SER22 |
| A | ILE23 |
| A | TRP105 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 703 |
| Chain | Residue |
| A | GLN56 |
| A | TYR57 |
| A | ASP58 |
| A | LYS302 |
| A | ASP432 |
| A | PRO438 |
| A | ILE439 |
| A | GLN440 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 704 |
| Chain | Residue |
| A | GLU99 |
| A | CYS389 |
| A | GLN393 |
| A | ALA407 |
| A | PHE410 |
| A | GLU411 |
| A | HOH1016 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 705 |
| Chain | Residue |
| A | LYS87 |
| A | ALA444 |
| A | GLY447 |
| A | GLY448 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 706 |
| Chain | Residue |
| A | PHE216 |
| A | ARG220 |
| A | PRO563 |
| A | THR567 |
| A | HIS610 |
| A | HOH1041 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 707 |
| Chain | Residue |
| A | ALA299 |
| A | ASP301 |
| A | ARG637 |
Functional Information from PROSITE/UniProt
| site_id | PS00081 |
| Number of Residues | 11 |
| Details | LIPOXYGENASE_2 Lipoxygenases iron-binding region signature 2. SHPLhVLLaPH |
| Chain | Residue | Details |
| A | SER399-HIS409 | |
| site_id | PS00711 |
| Number of Residues | 15 |
| Details | LIPOXYGENASE_1 Lipoxygenases iron-binding region signature 1. HEmfvHlAQTHLVsE |
| Chain | Residue | Details |
| A | HIS372-GLU386 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 5 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00726","evidenceCode":"ECO:0000255"}]} |
