4G01
ARA7-GDP-Ca2+/VPS9a
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005085 | molecular_function | guanyl-nucleotide exchange factor activity |
| A | 0016192 | biological_process | vesicle-mediated transport |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005525 | molecular_function | GTP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005768 | cellular_component | endosome |
| B | 0005769 | cellular_component | early endosome |
| B | 0005783 | cellular_component | endoplasmic reticulum |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006886 | biological_process | intracellular protein transport |
| B | 0007033 | biological_process | vacuole organization |
| B | 0007034 | biological_process | vacuolar transport |
| B | 0010008 | cellular_component | endosome membrane |
| B | 0012505 | cellular_component | endomembrane system |
| B | 0015031 | biological_process | protein transport |
| B | 0030139 | cellular_component | endocytic vesicle |
| B | 0031901 | cellular_component | early endosome membrane |
| B | 0032585 | cellular_component | multivesicular body membrane |
| B | 0036094 | molecular_function | small molecule binding |
| B | 0045324 | biological_process | late endosome to vacuole transport |
| B | 0140313 | molecular_function | molecular sequestering activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA A 300 |
| Chain | Residue |
| A | PRO182 |
| A | ASP185 |
| A | HOH404 |
| A | HOH410 |
| A | HOH485 |
| B | SER24 |
| B | GDP200 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE GDP B 200 |
| Chain | Residue |
| A | HOH404 |
| A | HOH485 |
| B | GLY20 |
| B | ALA21 |
| B | GLY22 |
| B | LYS23 |
| B | SER24 |
| B | SER25 |
| B | ASN123 |
| B | LYS124 |
| B | ASP126 |
| B | LEU127 |
| B | SER153 |
| B | ALA154 |
| B | LYS155 |
| B | HOH322 |
| B | HOH375 |
| A | ASN180 |
| A | CA300 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 144 |
| Details | Domain: {"description":"VPS9","evidences":[{"source":"PROSITE-ProRule","id":"PRU00550","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20833725","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2EFC","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Motif: {"description":"Effector region","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"20833725","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2EFC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2EFH","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
