Functional Information from GO Data
Chain | GOid | namespace | contents |
M | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
M | 0005829 | cellular_component | cytosol |
M | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
M | 0006221 | biological_process | pyrimidine nucleotide biosynthetic process |
M | 0016831 | molecular_function | carboxy-lyase activity |
M | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
N | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
N | 0005829 | cellular_component | cytosol |
N | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
N | 0006221 | biological_process | pyrimidine nucleotide biosynthetic process |
N | 0016831 | molecular_function | carboxy-lyase activity |
N | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 22 |
Details | BINDING SITE FOR RESIDUE BMP M 301 |
Chain | Residue |
M | ASP20 |
M | ALA203 |
M | HOH409 |
M | HOH410 |
M | HOH411 |
M | HOH412 |
M | HOH414 |
M | HOH427 |
M | HOH432 |
M | HOH455 |
M | HOH467 |
M | LYS42 |
N | ASP75 |
N | ILE76 |
N | THR79 |
M | ASP70 |
M | LYS72 |
M | MET126 |
M | SER127 |
M | PRO180 |
M | GLN185 |
M | GLY202 |
site_id | AC2 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE GOL M 302 |
Chain | Residue |
M | THR159 |
M | PRO161 |
M | GLY186 |
M | HOH516 |
N | ASN210 |
N | HOH420 |
N | HOH422 |
N | HOH469 |
site_id | AC3 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE GOL M 303 |
Chain | Residue |
M | PRO77 |
M | GLU78 |
N | HIS128 |
N | GLN185 |
N | HOH423 |
N | HOH433 |
site_id | AC4 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL M 304 |
Chain | Residue |
M | GLY52 |
M | MET53 |
M | ASP54 |
M | HOH521 |
N | SER50 |
N | GLY52 |
N | HOH464 |
site_id | AC5 |
Number of Residues | 21 |
Details | BINDING SITE FOR RESIDUE BMP N 301 |
Chain | Residue |
M | ASP75 |
M | ILE76 |
M | THR79 |
N | ASP20 |
N | LYS42 |
N | ASP70 |
N | LYS72 |
N | MET126 |
N | SER127 |
N | PRO180 |
N | GLN185 |
N | GLY202 |
N | ALA203 |
N | GOL302 |
N | HOH402 |
N | HOH403 |
N | HOH404 |
N | HOH411 |
N | HOH417 |
N | HOH436 |
N | HOH439 |
site_id | AC6 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE GOL N 302 |
Chain | Residue |
N | ALA184 |
N | GLN185 |
N | ALA203 |
N | TYR206 |
N | BMP301 |
N | HOH417 |
N | HOH433 |
N | HOH461 |
N | HOH548 |
N | HOH593 |
Functional Information from PROSITE/UniProt
site_id | PS00156 |
Number of Residues | 14 |
Details | OMPDECASE Orotidine 5'-phosphate decarboxylase active site. IIaDfKvaDIPeTN |
Chain | Residue | Details |
M | ILE67-ASN80 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Proton donor |
Chain | Residue | Details |
M | LYS72 | |
N | LYS72 | |
site_id | SWS_FT_FI2 |
Number of Residues | 14 |
Details | BINDING: |
Chain | Residue | Details |
M | ASP20 | |
N | ASP70 | |
N | SER127 | |
N | PRO180 | |
N | GLY202 | |
N | ALA203 | |
M | LYS42 | |
M | ASP70 | |
M | SER127 | |
M | PRO180 | |
M | GLY202 | |
M | ALA203 | |
N | ASP20 | |
N | LYS42 | |