Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 4UP A 301 |
| Chain | Residue |
| A | HIS46 |
| A | ASP192 |
| A | SER193 |
| A | GLN195 |
| A | SER198 |
| A | TRP218 |
| A | GLY221 |
| A | GLY229 |
| A | SIN303 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 302 |
| Chain | Residue |
| A | LYS53 |
| A | HIS95 |
| A | THR178 |
| A | LYS180 |
| A | MET181 |
| A | HOH424 |
| A | HOH584 |
| A | HOH600 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SIN A 303 |
| Chain | Residue |
| A | VAL30 |
| A | HIS46 |
| A | GLN195 |
| A | GLY196 |
| A | SER198 |
| A | 4UP301 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 304 |
| Chain | Residue |
| A | THR28 |
| A | TYR29 |
| A | TYR150 |
| A | GOL305 |
| A | HOH461 |
| A | HOH474 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 305 |
| Chain | Residue |
| A | THR28 |
| A | TYR29 |
| A | ASN67 |
| A | GOL304 |
| A | HOH627 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 306 |
| Chain | Residue |
| A | GLU5 |
| A | LYS142 |
| A | MET156 |
| A | GLN195 |
| A | GOL307 |
| A | HOH508 |
| A | HOH515 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 307 |
| Chain | Residue |
| A | GLU10 |
| A | ASN11 |
| A | LYS142 |
| A | SER145 |
| A | GLN195 |
| A | GLY221 |
| A | CYS222 |
| A | GOL306 |
| A | HOH439 |
| A | HOH459 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 308 |
| Chain | Residue |
| A | LYS75 |
| A | LYS106 |
| A | LYS225 |
| A | HOH462 |
| A | HOH502 |
| A | HOH545 |
| A | HOH630 |
| site_id | AC9 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE 15P A 309 |
| Chain | Residue |
| A | SER37 |
| A | PRO38 |
| A | CYS39 |
| A | TRP40 |
| A | LYS102 |
| A | GLN207 |
| A | THR245 |
| A | LYS246 |
| A | HOH432 |
| A | HOH610 |
| A | HOH642 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 310 |
| Chain | Residue |
| A | ARG20 |
| A | HIS22 |
| A | ARG23 |
| A | TYR51 |
| A | HOH590 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A 311 |
| Chain | Residue |
| A | TYR126 |
| A | ARG233 |
| A | HIS236 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A 312 |
| Chain | Residue |
| A | LYS180 |
| A | HIS236 |
| A | HOH440 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A 313 |
| Chain | Residue |
| A | THR179 |
| A | HOH584 |
| A | HOH600 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 314 |
| Chain | Residue |
| A | PRO52 |
| A | LEU81 |
| A | THR91 |
| A | GLU176 |
| A | HOH480 |
| A | HOH484 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A 315 |
| Chain | Residue |
| A | ARG21 |
| A | ARG23 |
| A | GLY24 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. ISATHC |
| Chain | Residue | Details |
| A | ILE42-CYS47 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPLV |
| Chain | Residue | Details |
| A | ASP192-VAL203 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | HIS46 | |
| A | ASP97 | |
| A | SER198 | |
| Chain | Residue | Details |
| A | SER145 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine |
| Chain | Residue | Details |
| A | GLN144 | |
