Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0039617 | cellular_component | T=3 icosahedral viral capsid |
| A | 0046718 | biological_process | symbiont entry into host cell |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0140267 | biological_process | symbiont entry into host cell via permeabilization of host membrane |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0039617 | cellular_component | T=3 icosahedral viral capsid |
| B | 0046718 | biological_process | symbiont entry into host cell |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0140267 | biological_process | symbiont entry into host cell via permeabilization of host membrane |
| C | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| C | 0039617 | cellular_component | T=3 icosahedral viral capsid |
| C | 0046718 | biological_process | symbiont entry into host cell |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0140267 | biological_process | symbiont entry into host cell via permeabilization of host membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 501 |
| Chain | Residue |
| A | ASP221 |
| A | GLY273 |
| A | HOH659 |
| B | ASP161 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 502 |
| Chain | Residue |
| A | ASP249 |
| A | GLU251 |
| B | ASP249 |
| C | ASP249 |
| C | GLU251 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE EPE A 503 |
| Chain | Residue |
| A | GLY258 |
| A | GLN260 |
| A | THR261 |
| A | PRO264 |
| A | ALA265 |
| A | ALA282 |
| A | GLU283 |
| C | GLN201 |
| C | PHE202 |
| C | PRO203 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA B 501 |
| Chain | Residue |
| B | ASP221 |
| B | GLY273 |
| B | HOH678 |
| C | THR157 |
| C | SER160 |
| C | ASP161 |
| C | GLU257 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 502 |
| Chain | Residue |
| B | SER102 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EPE B 503 |
| Chain | Residue |
| A | GLN201 |
| A | PRO203 |
| B | GLY258 |
| B | GLN260 |
| B | THR261 |
| B | PRO264 |
| B | ALA265 |
| B | GLU283 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA C 501 |
| Chain | Residue |
| A | ASP161 |
| C | ASP221 |
| C | GLY273 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 C 502 |
| Chain | Residue |
| A | SER211 |
| A | LEU213 |
| B | SER211 |
| B | SER212 |
| B | LEU213 |
| C | SER211 |
| C | SER212 |
| C | LEU213 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EPE C 503 |
| Chain | Residue |
| B | GLN201 |
| B | PHE202 |
| B | PRO203 |
| C | SER156 |
| C | GLY258 |
| C | GLN260 |
| C | THR261 |
| C | PRO264 |
| C | ALA265 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: ACT_SITE => ECO:0000305|PubMed:19553341 |
| Chain | Residue | Details |
| A | ASP75 | |
| B | ASP75 | |
| C | ASP75 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0007744|PDB:4FTS |
| Chain | Residue | Details |
| A | ASP161 | |
| B | ASP161 | |
| C | ASP161 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0007744|PDB:4FTB |
| Chain | Residue | Details |
| A | ASP221 | |
| A | GLY273 | |
| B | ASP221 | |
| B | GLY273 | |
| C | ASP221 | |
| C | GLY273 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0007744|PDB:4FSJ |
| Chain | Residue | Details |
| A | ASP249 | |
| A | GLU251 | |
| B | ASP249 | |
| B | GLU251 | |
| C | ASP249 | |
| C | GLU251 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | SITE: Cleavage; by autolysis => ECO:0000269|PubMed:1404613 |
| Chain | Residue | Details |
| A | THR363 | |
| B | THR363 | |
| C | THR363 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 9 |
| Details | SITE: Interaction with viral RNA genome => ECO:0000269|PubMed:9765417 |
| Chain | Residue | Details |
| A | PHE402 | |
| A | PHE405 | |
| A | PHE407 | |
| B | PHE402 | |
| B | PHE405 | |
| B | PHE407 | |
| C | PHE402 | |
| C | PHE405 | |
| C | PHE407 |
