4FSS
Crystal structure of a RAS p21 protein activator (RASA1) from Homo sapiens at 2.25 A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005096 | molecular_function | GTPase activator activity |
| A | 0043547 | biological_process | positive regulation of GTPase activity |
| A | 0046580 | biological_process | negative regulation of Ras protein signal transduction |
| B | 0005096 | molecular_function | GTPase activator activity |
| B | 0043547 | biological_process | positive regulation of GTPase activity |
| B | 0046580 | biological_process | negative regulation of Ras protein signal transduction |
| C | 0005096 | molecular_function | GTPase activator activity |
| C | 0043547 | biological_process | positive regulation of GTPase activity |
| C | 0046580 | biological_process | negative regulation of Ras protein signal transduction |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 A 1001 |
| Chain | Residue |
| A | ARG281 |
| A | HIS310 |
| C | ASP326 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 1002 |
| Chain | Residue |
| A | LYS292 |
| A | ASP295 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 401 |
| Chain | Residue |
| B | ARG281 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL C 401 |
| Chain | Residue |
| C | ASP295 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL C 402 |
| Chain | Residue |
| B | GLY340 |
| B | ARG341 |
| C | LYS292 |
| C | GLU327 |
| B | ARG285 |
| B | VAL339 |
