Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GLU B 100 |
| Chain | Residue |
| B | GLY27 |
| B | ALA28 |
| B | ASP29 |
| B | ASP30 |
| B | VAL47 |
| B | GLY48 |
| B | ILE101 |
| B | HOH738 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE ILE B 101 |
| Chain | Residue |
| A | ASP25 |
| A | ILE84 |
| B | GLY27 |
| B | GLY49 |
| B | GLU100 |
| C | ILE263 |
| F | ILE364 |
| F | HOH401 |
| A | LEU23 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 102 |
| Chain | Residue |
| B | ASP60 |
| B | HOH719 |
| B | HOH726 |
| B | HOH736 |
| B | HOH740 |
| B | HOH741 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 103 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 104 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 105 |
| Chain | Residue |
| A | THR4 |
| A | LEU5 |
| B | ALA95 |
| B | HOH706 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 101 |
| Chain | Residue |
| A | GLN2 |
| A | ILE3 |
| A | THR4 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 102 |
| Chain | Residue |
| A | PRO1 |
| A | ILE3 |
| A | VAL11 |
| A | HOH215 |
| A | HOH285 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 103 |
| Chain | Residue |
| A | THR12 |
| A | GLU65 |
| A | ALA67 |
| A | GLY68 |
| B | GLN18 |
| B | MET36 |
| B | SER37 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
| Chain | Residue | Details |
| B | ALA22-ILE33 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| B | ASP25 | |
| A | ASP25 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| B | PHE99 | |
| A | PHE99 | |
