Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004806 | molecular_function | triglyceride lipase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0016042 | biological_process | lipid catabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004806 | molecular_function | triglyceride lipase activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0016042 | biological_process | lipid catabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 401 |
| Chain | Residue |
| A | ASP61 |
| A | HIS81 |
| A | HIS87 |
| A | ASP238 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 402 |
| Chain | Residue |
| A | GOL411 |
| A | GLU22 |
| A | GLU23 |
| A | MET24 |
| A | PHE25 |
| A | PHE25 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 403 |
| Chain | Residue |
| A | HOH570 |
| A | HOH765 |
| B | HIS85 |
| B | THR237 |
| B | TYR242 |
| B | LYS251 |
| B | GOL411 |
| B | HOH604 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 404 |
| Chain | Residue |
| A | LYS329 |
| A | SER332 |
| A | HOH693 |
| A | HOH766 |
| A | HOH826 |
| A | HOH861 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE NA A 405 |
| Chain | Residue |
| A | GLU270 |
| A | THR272 |
| A | GLU284 |
| A | NA406 |
| A | HOH577 |
| A | HOH578 |
| A | HOH684 |
| A | HOH760 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 406 |
| Chain | Residue |
| A | NA405 |
| A | HOH578 |
| A | HOH742 |
| A | HOH743 |
| A | HOH760 |
| A | HOH967 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA A 407 |
| Chain | Residue |
| A | GLU202 |
| A | ARG214 |
| A | ARG215 |
| A | CL417 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 408 |
| Chain | Residue |
| A | THR353 |
| A | TYR354 |
| A | HOH546 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 409 |
| Chain | Residue |
| A | TRP60 |
| A | HIS81 |
| A | HIS85 |
| A | HOH509 |
| A | HOH514 |
| A | HOH534 |
| A | HOH592 |
| A | HOH779 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 410 |
| Chain | Residue |
| A | THR50 |
| A | GLN69 |
| A | LEU97 |
| A | HOH579 |
| A | HOH629 |
| A | HOH718 |
| A | HOH816 |
| site_id | BC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 411 |
| Chain | Residue |
| A | GLU22 |
| A | PHE25 |
| A | PHE25 |
| A | SER201 |
| A | GLU202 |
| A | VAL203 |
| A | GOL402 |
| A | HOH585 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 412 |
| Chain | Residue |
| A | GLU127 |
| A | GLY151 |
| A | HIS152 |
| A | HIS153 |
| A | ASN261 |
| site_id | BC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 413 |
| Chain | Residue |
| A | ARG303 |
| A | ASP310 |
| A | ASP311 |
| A | HOH507 |
| A | HOH617 |
| A | HOH858 |
| B | PHE90 |
| B | GLY91 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 414 |
| Chain | Residue |
| A | PHE25 |
| A | ALA192 |
| A | SER201 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 415 |
| Chain | Residue |
| A | GLY275 |
| A | LEU277 |
| A | THR278 |
| A | GLY279 |
| A | ASN280 |
| A | TYR282 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 416 |
| Chain | Residue |
| A | THR200 |
| A | THR200 |
| A | SER201 |
| A | SER201 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 417 |
| Chain | Residue |
| A | PHE206 |
| A | ARG215 |
| A | TYR224 |
| A | NA407 |
| site_id | BC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 418 |
| Chain | Residue |
| A | ARG227 |
| A | ARG214 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 419 |
| Chain | Residue |
| A | ARG34 |
| A | PRO366 |
| A | ASN367 |
| A | PRO368 |
| A | HOH875 |
| site_id | CC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A 420 |
| Chain | Residue |
| A | GLY286 |
| A | GLU360 |
| A | ASP365 |
| A | PRO366 |
| A | HOH666 |
| A | HOH747 |
| site_id | CC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 401 |
| Chain | Residue |
| B | ASP61 |
| B | HIS81 |
| B | HIS87 |
| B | ASP238 |
| site_id | CC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA B 402 |
| Chain | Residue |
| B | LYS329 |
| B | SER332 |
| B | HOH730 |
| B | HOH757 |
| B | HOH816 |
| site_id | CC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA B 403 |
| Chain | Residue |
| B | SER369 |
| B | HOH575 |
| B | HOH724 |
| B | HOH910 |
| site_id | CC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE NA B 404 |
| Chain | Residue |
| B | GLU270 |
| B | THR272 |
| B | GLU284 |
| B | HOH621 |
| B | HOH653 |
| B | HOH726 |
| B | HOH900 |
| site_id | CC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA B 405 |
| Chain | Residue |
| A | HOH727 |
| A | HOH884 |
| B | HOH746 |
| B | HOH918 |
| B | HOH929 |
| site_id | CC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA B 406 |
| Chain | Residue |
| B | HIS153 |
| B | ALA192 |
| B | HOH519 |
| B | HOH529 |
| B | HOH543 |
| B | HOH733 |
| site_id | CC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 407 |
| Chain | Residue |
| B | THR50 |
| B | GLN69 |
| B | TYR94 |
| B | GOL413 |
| B | HOH620 |
| B | HOH646 |
| B | HOH916 |
| site_id | DC1 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE GOL B 408 |
| Chain | Residue |
| B | GLY26 |
| B | PHE27 |
| B | LYS28 |
| B | GLY32 |
| B | GLY35 |
| B | ASP36 |
| B | GLU149 |
| B | GLY150 |
| B | GLY151 |
| B | HIS152 |
| B | HOH776 |
| B | HOH938 |
| site_id | DC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL B 409 |
| Chain | Residue |
| B | TYR199 |
| B | THR200 |
| B | GLU202 |
| B | ARG214 |
| B | ARG215 |
| B | GLN216 |
| B | PRO217 |
| B | HOH598 |
| B | HOH868 |
| site_id | DC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL B 410 |
| Chain | Residue |
| B | ASP7 |
| B | ALA8 |
| B | GLY105 |
| B | ARG106 |
| B | CL420 |
| B | HOH654 |
| B | HOH756 |
| B | HOH780 |
| B | HOH870 |
| B | HOH936 |
| site_id | DC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL B 411 |
| Chain | Residue |
| A | GOL403 |
| A | HOH570 |
| A | HOH765 |
| B | TRP60 |
| B | HIS81 |
| B | HIS85 |
| B | HOH506 |
| B | HOH541 |
| B | HOH584 |
| site_id | DC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 412 |
| Chain | Residue |
| B | TYR67 |
| B | LYS102 |
| B | HIS152 |
| B | HOH549 |
| B | HOH578 |
| B | HOH643 |
| B | HOH775 |
| site_id | DC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL B 413 |
| Chain | Residue |
| B | ARG21 |
| B | GLU38 |
| B | TYR49 |
| B | THR50 |
| B | LEU97 |
| B | GOL407 |
| B | HOH700 |
| B | HOH708 |
| B | HOH762 |
| B | HOH826 |
| site_id | DC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE GOL B 414 |
| Chain | Residue |
| B | THR353 |
| B | HOH527 |
| site_id | DC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 415 |
| Chain | Residue |
| B | ARG34 |
| B | ARG373 |
| B | HOH611 |
| B | HOH808 |
| site_id | DC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 416 |
| Chain | Residue |
| B | TRP60 |
| B | SER130 |
| B | GLU132 |
| B | TRP255 |
| B | HOH584 |
| B | HOH640 |
| B | HOH932 |
| site_id | EC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 417 |
| Chain | Residue |
| B | PHE267 |
| B | TYR354 |
| B | PHE375 |
| B | ARG378 |
| B | GLN382 |
| B | HOH915 |
| site_id | EC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL B 418 |
| Chain | Residue |
| B | LYS185 |
| B | GLU189 |
| B | SER195 |
| B | HOH571 |
| B | HOH608 |
| B | HOH627 |
| B | HOH841 |
| B | HOH880 |
| B | HOH890 |
| site_id | EC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL B 419 |
| Chain | Residue |
| B | GLY275 |
| B | LEU277 |
| B | THR278 |
| B | GLY279 |
| B | ASN280 |
| B | TYR282 |
| site_id | EC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 420 |
| Chain | Residue |
| B | ARG106 |
| B | GOL410 |
| site_id | EC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL B 421 |
| Chain | Residue |
| B | LEU213 |
| B | ARG214 |
| B | GLN216 |
| B | ARG227 |
| site_id | EC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL B 422 |
| Chain | Residue |
| B | ARG34 |
| B | PRO366 |
| B | ASN367 |
| B | PRO368 |
| B | HOH648 |
| B | HOH810 |
| site_id | EC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 423 |
| Chain | Residue |
| B | LEU126 |
| B | HIS153 |
| B | PHE154 |
| B | VAL155 |
| B | HOH725 |
| site_id | EC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA B 424 |
| Chain | Residue |
| B | GLY286 |
| B | GLU360 |
| B | ASP365 |
| B | PRO366 |
| B | HOH660 |
| B | HOH691 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Nucleophile => ECO:0000269|Ref.3 |
| Chain | Residue | Details |
| A | SER113 | |
| B | SER113 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | ACT_SITE: Charge relay system => ECO:0000269|Ref.3 |
| Chain | Residue | Details |
| A | ASP317 | |
| A | HIS358 | |
| B | ASP317 | |
| B | HIS358 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | BINDING: BINDING => ECO:0000269|Ref.3 |
| Chain | Residue | Details |
| B | GLY286 | |
| B | GLU360 | |
| B | ASP365 | |
| B | PRO366 | |
| A | GLY286 | |
| A | GLU360 | |
| A | ASP365 | |
| A | PRO366 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | ASP357 | |
| B | ASP357 | |
