4FI1
Crystal structure of scCK2 alpha in complex with ATP
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000028 | biological_process | ribosomal small subunit assembly |
A | 0004672 | molecular_function | protein kinase activity |
A | 0004674 | molecular_function | protein serine/threonine kinase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005524 | molecular_function | ATP binding |
A | 0005634 | cellular_component | nucleus |
A | 0005654 | cellular_component | nucleoplasm |
A | 0005730 | cellular_component | nucleolus |
A | 0005829 | cellular_component | cytosol |
A | 0005956 | cellular_component | protein kinase CK2 complex |
A | 0006338 | biological_process | chromatin remodeling |
A | 0006356 | biological_process | regulation of transcription by RNA polymerase I |
A | 0006359 | biological_process | regulation of transcription by RNA polymerase III |
A | 0006468 | biological_process | protein phosphorylation |
A | 0006974 | biological_process | DNA damage response |
A | 0007535 | biological_process | donor selection |
A | 0016310 | biological_process | phosphorylation |
A | 0030490 | biological_process | maturation of SSU-rRNA |
A | 0032040 | cellular_component | small-subunit processome |
A | 0032545 | cellular_component | CURI complex |
A | 0034456 | cellular_component | UTP-C complex |
A | 0042790 | biological_process | nucleolar large rRNA transcription by RNA polymerase I |
A | 0044024 | molecular_function | histone H2AS1 kinase activity |
A | 0051726 | biological_process | regulation of cell cycle |
A | 0060962 | biological_process | regulation of ribosomal protein gene transcription by RNA polymerase II |
A | 0106310 | molecular_function | protein serine kinase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE MG A 401 |
Chain | Residue |
A | ASN200 |
A | ASP214 |
A | ATP403 |
A | HOH622 |
site_id | AC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE MG A 402 |
Chain | Residue |
A | HIS187 |
A | ALA354 |
A | HOH523 |
A | HOH554 |
site_id | AC3 |
Number of Residues | 23 |
Details | BINDING SITE FOR RESIDUE ATP A 403 |
Chain | Residue |
A | GLY49 |
A | LYS50 |
A | TYR51 |
A | SER52 |
A | VAL54 |
A | VAL67 |
A | LYS69 |
A | ILE134 |
A | GLU153 |
A | VAL155 |
A | ASP195 |
A | HIS199 |
A | ASN200 |
A | MET202 |
A | ILE213 |
A | ASP214 |
A | MG401 |
A | SO4407 |
A | HOH507 |
A | HOH548 |
A | HOH563 |
A | HOH622 |
A | ARG48 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 A 404 |
Chain | Residue |
A | ARG268 |
A | LYS317 |
A | ARG321 |
A | ASN324 |
A | ASP325 |
site_id | AC5 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 A 405 |
Chain | Residue |
A | ARG161 |
A | LYS166 |
A | HOH613 |
site_id | AC6 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 A 406 |
Chain | Residue |
A | ARG81 |
A | ARG194 |
A | ASN228 |
A | VAL231 |
A | HOH513 |
site_id | AC7 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 A 407 |
Chain | Residue |
A | LYS197 |
A | HIS199 |
A | ATP403 |
A | HOH622 |
A | HOH632 |
site_id | AC8 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE SO4 A 408 |
Chain | Residue |
A | ARG234 |
A | ASN277 |
A | HOH589 |
site_id | AC9 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE SO4 A 409 |
Chain | Residue |
A | ARG316 |
A | PRO318 |
A | TRP319 |
A | HIS320 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 24 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. VGRGKYSEVFqGvkldskvk..........IVIK |
Chain | Residue | Details |
A | VAL46-LYS69 |
site_id | PS00108 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. ImHrDVKphNVMI |
Chain | Residue | Details |
A | ILE191-ILE203 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00159, ECO:0000255|PROSITE-ProRule:PRU10027 |
Chain | Residue | Details |
A | ASP195 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00159 |
Chain | Residue | Details |
A | VAL46 | |
A | LYS69 |