4FH5
Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity - MgUTP bound
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE UTP A 401 |
| Chain | Residue |
| A | PHE88 |
| A | LYS197 |
| A | SER211 |
| A | TYR212 |
| A | HIS336 |
| A | MG402 |
| A | HOH501 |
| A | HOH523 |
| A | HOH524 |
| A | HOH531 |
| A | HOH538 |
| A | GLY89 |
| A | HOH544 |
| A | HOH551 |
| A | HOH596 |
| A | HOH597 |
| A | HOH600 |
| A | SER90 |
| A | ASP101 |
| A | ASP103 |
| A | ALA168 |
| A | ASN171 |
| A | THR172 |
| A | LYS193 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 402 |
| Chain | Residue |
| A | ASP101 |
| A | ASP103 |
| A | UTP401 |
| A | HOH551 |
| A | HOH597 |
| A | HOH600 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22608966, ECO:0000269|PubMed:22751018, ECO:0000269|PubMed:22885303, ECO:0000269|PubMed:24322298 |
| Chain | Residue | Details |
| A | SER90 | |
| A | LYS193 | |
| A | LYS197 | |
| A | HIS336 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22885303 |
| Chain | Residue | Details |
| A | ASP101 | |
| A | ASP103 | |
| A | SER211 | |
| A | ARG340 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22608966, ECO:0000269|PubMed:22751018, ECO:0000269|PubMed:22885303 |
| Chain | Residue | Details |
| A | ALA168 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:22885303, ECO:0000269|PubMed:24322298 |
| Chain | Residue | Details |
| A | ASN171 |
