4FH2

Structure of s70c beta-lactamase bound to sulbactam

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008800	molecular_function	beta-lactamase activity
A	0016787	molecular_function	hydrolase activity
A	0017001	biological_process	antibiotic catabolic process
A	0030655	biological_process	beta-lactam antibiotic catabolic process
A	0046677	biological_process	response to antibiotic

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	BINDING SITE FOR RESIDUE MA4 A 301

Chain	Residue
A	ARG93
A	ILE263
A	ALA280
A	ALA284
A	HOH415
A	HOH475
A	HOH585
A	LYS94
A	ILE95
A	HIS96
A	ARG98
A	VAL224
A	PRO226
A	ILE231
A	VAL261

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MA4 A 302

Chain	Residue
A	ARG244
A	ILE279

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site_id	AC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE 0RN A 303

Chain	Residue
A	CYS70
A	SER130
A	VAL216
A	THR235
A	GLY236
A	ALA237
A	ARG244
A	HOH535
A	HOH600

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Nucleophile; acyl-ester intermediate","evidences":[{"source":"UniProtKB","id":"A0A5R8T042","evidenceCode":"ECO:0000250"},{"source":"PROSITE-ProRule","id":"PRU10101","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Proton acceptor"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"A0A5R8T042","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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