Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 501 |
| Chain | Residue |
| A | TYR99 |
| A | GLN101 |
| A | GLN103 |
| A | LYS266 |
| A | HOH782 |
| A | HOH795 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 502 |
| Chain | Residue |
| A | ARG109 |
| A | HOH771 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 503 |
| Chain | Residue |
| A | PRO71 |
| A | SER106 |
| A | HIS193 |
| A | PRO195 |
| A | HOH645 |
| A | HOH819 |
| A | HOH961 |
| A | SER70 |
| site_id | AC4 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE 0U4 A 504 |
| Chain | Residue |
| A | GLY59 |
| A | GLN60 |
| A | GLY61 |
| A | LEU78 |
| A | ASP80 |
| A | GLY82 |
| A | SER83 |
| A | TYR119 |
| A | THR120 |
| A | GLN121 |
| A | PHE156 |
| A | TRP163 |
| A | TYR246 |
| A | ASP276 |
| A | SER277 |
| A | GLY278 |
| A | THR279 |
| A | THR280 |
| A | ASN281 |
| A | ARG283 |
| A | SER373 |
| A | THR377 |
| A | ALA383 |
| A | URE506 |
| A | HOH751 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE URE A 505 |
| Chain | Residue |
| A | HOH672 |
| A | HOH681 |
| A | HOH699 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE URE A 506 |
| Chain | Residue |
| A | 0U4504 |
| A | HOH635 |
| A | HOH884 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ILVDTGSSNFAV |
| Chain | Residue | Details |
| A | ILE77-VAL88 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP80 | |
| A | ASP276 | |
| Chain | Residue | Details |
| A | LYS113 | |
| A | LYS262 | |
| A | LYS266 | |
| A | LYS272 | |
| A | LYS286 | |
| A | LYS287 | |
| A | LYS294 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN140 | |
| A | ASN159 | |
| A | ASN210 | |
| A | ASN341 | |
