4F5T

Crystal Structure of Equine Serum Albumin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0005504	molecular_function	fatty acid binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0008289	molecular_function	lipid binding
A	0009267	biological_process	cellular response to starvation
A	0015643	molecular_function	toxic substance binding
A	0019825	molecular_function	oxygen binding
A	0030170	molecular_function	pyridoxal phosphate binding
A	0031667	biological_process	response to nutrient levels
A	0032991	cellular_component	protein-containing complex
A	0046872	molecular_function	metal ion binding
A	0051902	biological_process	negative regulation of mitochondrial depolarization
A	0072732	biological_process	cellular response to calcium ion starvation
A	1903981	molecular_function	enterobactin binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACT A 601

Chain	Residue
A	LEU218
A	LYS221
A	PHE222
A	ALA290
A	SO4609

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE ACT A 602

Chain	Residue
A	GOL615
A	HOH919
A	HOH920
A	ASN390
A	LEU406
A	ARG409
A	TYR410

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACT A 603

Chain	Residue
A	SER191
A	GLU195
A	LYS198
A	SO4609
A	HOH933

---

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE ACT A 604

Chain	Residue
A	TYR30
A	HIS67
A	GLY71
A	LEU74
A	GLU95
A	ARG98
A	ASN99
A	HOH783

---

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACT A 605

Chain	Residue
A	HIS105
A	LYS106
A	ASP107

---

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE ACT A 606

Chain	Residue
A	LYS17
A	HIS18

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 607

Chain	Residue
A	LYS194
A	ARG217
A	ALA290
A	GLU291
A	HOH868
A	HOH911

---

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 608

Chain	Residue
A	SER341
A	SER343
A	ARG347
A	PRO383
A	GLU449
A	ARG484
A	HOH861

---

site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 609

Chain	Residue
A	TYR149
A	HIS241
A	ARG256
A	ALA290
A	ACT601
A	ACT603
A	HOH849

---

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 610

Chain	Residue
A	HIS287
A	GLU291
A	HOH801

---

site_id	BC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 611

Chain	Residue
A	ASP108
A	ARG144
A	HIS145
A	PRO146
A	TYR147
A	SER192
A	ARG458

---

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 612

Chain	Residue
A	LYS412
A	THR539
A	LYS540
A	HOH741
A	HOH806
A	HOH923

---

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 613

Chain	Residue
A	ALA303
A	LEU304
A	ALA305
A	ARG336
A	GLU561

---

site_id	BC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 614

Chain	Residue
A	SER418
A	THR419
A	LYS499
A	LYS533
A	HOH880
A	HOH897
A	HOH898

---

site_id	BC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 615

Chain	Residue
A	ASN390
A	PHE402
A	LEU429
A	GLY433
A	SER448
A	ACT602

---

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 616

Chain	Residue
A	GLU470
A	LYS474
A	LYS535
A	ALA583

---

site_id	BC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 617

Chain	Residue
A	CYS460
A	GLU464
A	CYS476
A	GLN542
A	HOH930
A	HOH934

---

site_id	BC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE GOL A 618

Chain	Residue
A	LYS114
A	HIS266
A	HOH960

---

Functional Information from PROSITE/UniProt

site_id	PS00212
Number of Residues	25
Details	ALBUMIN_1 Albumin domain signature. YkadfteCCpaDdklaCLipkldaL

Chain	Residue	Details
A	TYR160-LEU184
A	TYR352-PHE376
A	PHE550-LEU574

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	192
Details	Domain: {"description":"Albumin 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00769","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	197
Details	Domain: {"description":"Albumin 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00769","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P02770","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P02769","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28567254","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5IIH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	5
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P02768","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	3
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P02768","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	Modified residue: {"description":"N6-methyllysine","evidences":[{"source":"UniProtKB","id":"P02768","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P02770","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P07724","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---