4F4K
DNA Polymerase I Large Fragment Complex 6
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| A | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| A | 0006260 | biological_process | DNA replication |
| A | 0006261 | biological_process | DNA-templated DNA replication |
| A | 0008408 | molecular_function | 3'-5' exonuclease activity |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| D | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| D | 0006260 | biological_process | DNA replication |
| D | 0006261 | biological_process | DNA-templated DNA replication |
| D | 0008408 | molecular_function | 3'-5' exonuclease activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 901 |
| Chain | Residue |
| A | ARG779 |
| A | ASN780 |
| A | HOH1163 |
| A | HOH1239 |
| D | PRO424 |
| D | HOH1421 |
| site_id | AC2 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE DG3 D 901 |
| Chain | Residue |
| D | SER655 |
| D | GLN656 |
| D | ILE657 |
| D | GLU658 |
| D | HIS682 |
| D | ARG702 |
| D | LYS706 |
| D | TYR710 |
| D | TYR714 |
| D | ASP830 |
| D | MN902 |
| D | HOH1023 |
| D | HOH1065 |
| D | HOH1197 |
| D | HOH1245 |
| D | HOH1273 |
| D | HOH1280 |
| D | HOH1458 |
| E | DDG29 |
| F | DT3 |
| F | DC4 |
| D | ARG615 |
| D | ASP653 |
| D | TYR654 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MN D 902 |
| Chain | Residue |
| D | ASP653 |
| D | TYR654 |
| D | ASP830 |
| D | DG3901 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 D 903 |
| Chain | Residue |
| D | LYS298 |
| D | MET299 |
| D | ALA300 |
| D | ARG343 |
| D | ARG677 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 D 904 |
| Chain | Residue |
| A | LYS730 |
| D | ARG517 |
| D | GLU569 |
| D | ASN573 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MPD D 905 |
| Chain | Residue |
| A | HOH1089 |
| A | HOH1269 |
| D | LEU766 |
| D | HOH1087 |
| D | HOH1358 |
| D | HOH1605 |
Functional Information from PROSITE/UniProt
| site_id | PS00447 |
| Number of Residues | 20 |
| Details | DNA_POLYMERASE_A DNA polymerase family A signature. RrqAKavnYGivYgiSdygL |
| Chain | Residue | Details |
| A | ARG702-LEU721 |
