4F2D

Crystal Structure of Escherichia coli L-arabinose Isomerase (ECAI) complexed with Ribitol

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005996	biological_process	monosaccharide metabolic process
A	0008733	molecular_function	L-arabinose isomerase activity
A	0016853	molecular_function	isomerase activity
A	0016861	molecular_function	intramolecular oxidoreductase activity, interconverting aldoses and ketoses
A	0019568	biological_process	arabinose catabolic process
A	0019569	biological_process	L-arabinose catabolic process to xylulose 5-phosphate
A	0030145	molecular_function	manganese ion binding
A	0046872	molecular_function	metal ion binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005996	biological_process	monosaccharide metabolic process
B	0008733	molecular_function	L-arabinose isomerase activity
B	0016853	molecular_function	isomerase activity
B	0016861	molecular_function	intramolecular oxidoreductase activity, interconverting aldoses and ketoses
B	0019568	biological_process	arabinose catabolic process
B	0019569	biological_process	L-arabinose catabolic process to xylulose 5-phosphate
B	0030145	molecular_function	manganese ion binding
B	0046872	molecular_function	metal ion binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005996	biological_process	monosaccharide metabolic process
C	0008733	molecular_function	L-arabinose isomerase activity
C	0016853	molecular_function	isomerase activity
C	0016861	molecular_function	intramolecular oxidoreductase activity, interconverting aldoses and ketoses
C	0019568	biological_process	arabinose catabolic process
C	0019569	biological_process	L-arabinose catabolic process to xylulose 5-phosphate
C	0030145	molecular_function	manganese ion binding
C	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN A 601

Chain	Residue
A	GLU306
A	GLU333
A	HIS350
A	HIS450
A	RB0602

---

site_id	AC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE RB0 A 602

Chain	Residue
A	TYR335
A	HIS449
A	HIS450
A	MN601
A	HOH788
B	GLN16
B	LEU18
B	TYR19
B	PHE83
B	GLN125
B	HIS128
A	MSE185
A	PHE279
A	GLU306
A	GLU333

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN B 601

Chain	Residue
B	GLU306
B	GLU333
B	HIS350
B	HIS450
B	RB0602

---

site_id	AC4
Number of Residues	13
Details	BINDING SITE FOR RESIDUE RB0 B 602

Chain	Residue
B	MSE185
B	PHE279
B	GLU306
B	GLU333
B	HIS449
B	HIS450
B	MN601
B	HOH776
C	GLN16
C	TYR19
C	PHE83
C	GLN125
C	HIS128

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACY B 603

Chain	Residue
A	TRP491
A	VAL494
B	TRP491
B	VAL494
C	TRP491
C	VAL494

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN C 601

Chain	Residue
C	GLU306
C	GLU333
C	HIS350
C	HIS450
C	RB0602

---

site_id	AC7
Number of Residues	9
Details	BINDING SITE FOR RESIDUE RB0 C 602

Chain	Residue
A	GLN125
A	HIS128
C	MSE185
C	PHE279
C	GLU306
C	GLU333
C	HIS449
C	HIS450
C	MN601

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING:

Chain	Residue	Details
A	GLU306
C	GLU333
C	HIS350
C	HIS450
A	GLU333
A	HIS350
A	HIS450
B	GLU306
B	GLU333
B	HIS350
B	HIS450
C	GLU306

---