4F1E
The Crystal Structure of a Human MitoNEET mutant with Asp 67 replaced by a Gly
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0010506 | biological_process | regulation of autophagy |
A | 0043231 | cellular_component | intracellular membrane-bounded organelle |
A | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
B | 0010506 | biological_process | regulation of autophagy |
B | 0043231 | cellular_component | intracellular membrane-bounded organelle |
B | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
C | 0010506 | biological_process | regulation of autophagy |
C | 0043231 | cellular_component | intracellular membrane-bounded organelle |
C | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
D | 0010506 | biological_process | regulation of autophagy |
D | 0043231 | cellular_component | intracellular membrane-bounded organelle |
D | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
E | 0010506 | biological_process | regulation of autophagy |
E | 0043231 | cellular_component | intracellular membrane-bounded organelle |
E | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
F | 0010506 | biological_process | regulation of autophagy |
F | 0043231 | cellular_component | intracellular membrane-bounded organelle |
F | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
G | 0010506 | biological_process | regulation of autophagy |
G | 0043231 | cellular_component | intracellular membrane-bounded organelle |
G | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
H | 0010506 | biological_process | regulation of autophagy |
H | 0043231 | cellular_component | intracellular membrane-bounded organelle |
H | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
I | 0010506 | biological_process | regulation of autophagy |
I | 0043231 | cellular_component | intracellular membrane-bounded organelle |
I | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
J | 0010506 | biological_process | regulation of autophagy |
J | 0043231 | cellular_component | intracellular membrane-bounded organelle |
J | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
K | 0010506 | biological_process | regulation of autophagy |
K | 0043231 | cellular_component | intracellular membrane-bounded organelle |
K | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
L | 0010506 | biological_process | regulation of autophagy |
L | 0043231 | cellular_component | intracellular membrane-bounded organelle |
L | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
M | 0010506 | biological_process | regulation of autophagy |
M | 0043231 | cellular_component | intracellular membrane-bounded organelle |
M | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
N | 0010506 | biological_process | regulation of autophagy |
N | 0043231 | cellular_component | intracellular membrane-bounded organelle |
N | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
O | 0010506 | biological_process | regulation of autophagy |
O | 0043231 | cellular_component | intracellular membrane-bounded organelle |
O | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
P | 0010506 | biological_process | regulation of autophagy |
P | 0043231 | cellular_component | intracellular membrane-bounded organelle |
P | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
Q | 0010506 | biological_process | regulation of autophagy |
Q | 0043231 | cellular_component | intracellular membrane-bounded organelle |
Q | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
R | 0010506 | biological_process | regulation of autophagy |
R | 0043231 | cellular_component | intracellular membrane-bounded organelle |
R | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FES A 201 |
Chain | Residue |
A | CYS72 |
A | ARG73 |
A | CYS74 |
A | CYS83 |
A | ASP84 |
A | ALA86 |
A | HIS87 |
A | PRO100 |
site_id | AC2 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE FES B 201 |
Chain | Residue |
B | ARG73 |
B | CYS74 |
B | CYS83 |
B | ASP84 |
B | ALA86 |
B | HIS87 |
B | CYS72 |
site_id | AC3 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FES C 201 |
Chain | Residue |
C | CYS72 |
C | ARG73 |
C | CYS74 |
C | SER77 |
C | CYS83 |
C | ASP84 |
C | ALA86 |
C | HIS87 |
site_id | AC4 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FES D 500 |
Chain | Residue |
D | CYS72 |
D | ARG73 |
D | CYS74 |
D | SER77 |
D | CYS83 |
D | ASP84 |
D | ALA86 |
D | HIS87 |
site_id | AC5 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FES E 201 |
Chain | Residue |
E | CYS72 |
E | ARG73 |
E | CYS74 |
E | CYS83 |
E | ASP84 |
E | GLY85 |
E | ALA86 |
E | HIS87 |
site_id | AC6 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE FES F 201 |
Chain | Residue |
F | CYS72 |
F | ARG73 |
F | CYS74 |
F | CYS83 |
F | ASP84 |
F | ALA86 |
F | HIS87 |
site_id | AC7 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FES G 201 |
Chain | Residue |
G | CYS72 |
G | ARG73 |
G | CYS74 |
G | CYS83 |
G | ASP84 |
G | GLY85 |
G | ALA86 |
G | HIS87 |
site_id | AC8 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FES H 201 |
Chain | Residue |
H | CYS72 |
H | ARG73 |
H | CYS74 |
H | SER77 |
H | CYS83 |
H | ASP84 |
H | ALA86 |
H | HIS87 |
site_id | AC9 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FES I 201 |
Chain | Residue |
I | CYS72 |
I | ARG73 |
I | CYS74 |
I | CYS83 |
I | ASP84 |
I | GLY85 |
I | ALA86 |
I | HIS87 |
site_id | BC1 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FES J 201 |
Chain | Residue |
J | CYS72 |
J | ARG73 |
J | CYS74 |
J | CYS83 |
J | ASP84 |
J | GLY85 |
J | ALA86 |
J | HIS87 |
site_id | BC2 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FES K 201 |
Chain | Residue |
K | CYS72 |
K | ARG73 |
K | CYS74 |
K | CYS83 |
K | ASP84 |
K | GLY85 |
K | ALA86 |
K | HIS87 |
site_id | BC3 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FES L 201 |
Chain | Residue |
L | CYS72 |
L | ARG73 |
L | CYS74 |
L | CYS83 |
L | ASP84 |
L | GLY85 |
L | ALA86 |
L | HIS87 |
site_id | BC4 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE FES M 201 |
Chain | Residue |
M | ASP84 |
M | GLY85 |
M | ALA86 |
M | HIS87 |
M | CYS72 |
M | ARG73 |
M | CYS74 |
M | SER77 |
M | CYS83 |
site_id | BC5 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE FES N 201 |
Chain | Residue |
N | CYS72 |
N | ARG73 |
N | CYS74 |
N | CYS83 |
N | ASP84 |
N | ALA86 |
N | HIS87 |
site_id | BC6 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE FES O 201 |
Chain | Residue |
O | CYS72 |
O | ARG73 |
O | CYS74 |
O | CYS83 |
O | ASP84 |
O | ALA86 |
O | HIS87 |
site_id | BC7 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FES P 201 |
Chain | Residue |
P | CYS72 |
P | ARG73 |
P | CYS74 |
P | SER77 |
P | CYS83 |
P | ASP84 |
P | ALA86 |
P | HIS87 |
site_id | BC8 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE FES Q 201 |
Chain | Residue |
Q | CYS72 |
Q | ARG73 |
Q | CYS74 |
Q | CYS83 |
Q | ASP84 |
Q | ALA86 |
Q | HIS87 |
site_id | BC9 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FES R 201 |
Chain | Residue |
R | CYS72 |
R | ARG73 |
R | CYS74 |
R | SER77 |
R | CYS83 |
R | ASP84 |
R | ALA86 |
R | HIS87 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 18 |
Details | Active site: {"description":"Schiff-base intermediate with pyridoxal 5'-phosphate","evidences":[{"source":"PubMed","id":"36194135","evidenceCode":"ECO:0000269"}]} |
Chain | Residue | Details |
site_id | SWS_FT_FI2 |
Number of Residues | 72 |
Details | Binding site: {"evidences":[{"source":"PubMed","id":"17766439","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17766440","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17905743","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2QD0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2QH7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2R13","evidenceCode":"ECO:0007744"}]} |
Chain | Residue | Details |
site_id | SWS_FT_FI3 |
Number of Residues | 54 |
Details | Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q91WS0","evidenceCode":"ECO:0000250"}]} |
Chain | Residue | Details |
site_id | SWS_FT_FI4 |
Number of Residues | 118 |
Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"25621951","evidenceCode":"ECO:0000269"}]} |
Chain | Residue | Details |
site_id | SWS_FT_FI5 |
Number of Residues | 54 |
Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"PubMed","id":"25621951","evidenceCode":"ECO:0000269"}]} |
Chain | Residue | Details |