4EZD
Crystal Structure of the UT-B Urea Transporter from Bos Taurus Bound to Selenourea
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0015204 | molecular_function | urea transmembrane transporter activity |
| A | 0015265 | molecular_function | urea channel activity |
| A | 0016020 | cellular_component | membrane |
| A | 0016323 | cellular_component | basolateral plasma membrane |
| A | 0071918 | biological_process | urea transmembrane transport |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0015204 | molecular_function | urea transmembrane transporter activity |
| B | 0015265 | molecular_function | urea channel activity |
| B | 0016020 | cellular_component | membrane |
| B | 0016323 | cellular_component | basolateral plasma membrane |
| B | 0071918 | biological_process | urea transmembrane transport |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0015204 | molecular_function | urea transmembrane transporter activity |
| C | 0015265 | molecular_function | urea channel activity |
| C | 0016020 | cellular_component | membrane |
| C | 0016323 | cellular_component | basolateral plasma membrane |
| C | 0071918 | biological_process | urea transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 480 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| B | GLY237-ILE257 | |
| B | GLY279-LEU299 | |
| B | LEU305-MET325 | |
| B | VAL327-LEU347 | |
| C | ILE61-LEU81 | |
| C | PRO85-LEU105 | |
| C | ALA111-TYR131 | |
| C | PHE138-ALA158 | |
| C | GLY237-ILE257 | |
| C | GLY279-LEU299 | |
| C | LEU305-MET325 | |
| C | VAL327-LEU347 | |
| A | ILE61-LEU81 | |
| A | PRO85-LEU105 | |
| A | ALA111-TYR131 | |
| A | PHE138-ALA158 | |
| A | GLY237-ILE257 | |
| A | GLY279-LEU299 | |
| A | LEU305-MET325 | |
| A | VAL327-LEU347 | |
| B | ILE61-LEU81 | |
| B | PRO85-LEU105 | |
| B | ALA111-TYR131 | |
| B | PHE138-ALA158 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | SITE: Important for channel permeability => ECO:0000269|PubMed:22733730 |
| Chain | Residue | Details |
| A | THR334 | |
| B | THR334 | |
| C | THR334 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN206 | |
| B | ASN206 | |
| C | ASN206 |
