4EQL
Crystal Structure of GH3.12 in complex with AMP and salicylate
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005515 | molecular_function | protein binding |
A | 0006952 | biological_process | defense response |
A | 0009626 | biological_process | plant-type hypersensitive response |
A | 0009863 | biological_process | salicylic acid mediated signaling pathway |
A | 0010112 | biological_process | regulation of systemic acquired resistance |
A | 0016046 | biological_process | detection of fungus |
A | 0016874 | molecular_function | ligase activity |
A | 0018874 | biological_process | benzoate metabolic process |
A | 0034052 | biological_process | positive regulation of plant-type hypersensitive response |
A | 0042742 | biological_process | defense response to bacterium |
A | 0052625 | molecular_function | 4-aminobenzoate amino acid synthetase activity |
A | 0052626 | molecular_function | benzoate amino acid synthetase activity |
A | 0052627 | molecular_function | vanillate amino acid synthetase activity |
A | 0052628 | molecular_function | 4-hydroxybenzoate amino acid synthetase activity |
A | 0071456 | biological_process | cellular response to hypoxia |
B | 0005515 | molecular_function | protein binding |
B | 0006952 | biological_process | defense response |
B | 0009626 | biological_process | plant-type hypersensitive response |
B | 0009863 | biological_process | salicylic acid mediated signaling pathway |
B | 0010112 | biological_process | regulation of systemic acquired resistance |
B | 0016046 | biological_process | detection of fungus |
B | 0016874 | molecular_function | ligase activity |
B | 0018874 | biological_process | benzoate metabolic process |
B | 0034052 | biological_process | positive regulation of plant-type hypersensitive response |
B | 0042742 | biological_process | defense response to bacterium |
B | 0052625 | molecular_function | 4-aminobenzoate amino acid synthetase activity |
B | 0052626 | molecular_function | benzoate amino acid synthetase activity |
B | 0052627 | molecular_function | vanillate amino acid synthetase activity |
B | 0052628 | molecular_function | 4-hydroxybenzoate amino acid synthetase activity |
B | 0071456 | biological_process | cellular response to hypoxia |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE AMP A 601 |
Chain | Residue |
A | SER95 |
A | TYR347 |
A | ASP398 |
A | PHE414 |
A | ARG417 |
A | LYS428 |
A | SAL602 |
A | HOH764 |
A | HOH1267 |
A | SER96 |
A | VAL299 |
A | THR301 |
A | THR324 |
A | TYR325 |
A | GLY326 |
A | SER327 |
A | SER328 |
site_id | AC2 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE SAL A 602 |
Chain | Residue |
A | TYR120 |
A | ARG123 |
A | THR161 |
A | ILE217 |
A | THR324 |
A | GLY326 |
A | AMP601 |
A | HOH737 |
A | HOH1066 |
A | HOH1132 |
site_id | AC3 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE AMP B 601 |
Chain | Residue |
B | SER95 |
B | SER96 |
B | VAL299 |
B | THR301 |
B | THR324 |
B | TYR325 |
B | GLY326 |
B | SER327 |
B | SER328 |
B | TYR347 |
B | ASP398 |
B | PHE414 |
B | ARG417 |
B | SAL602 |
B | HOH864 |
B | HOH886 |
B | HOH1266 |
site_id | AC4 |
Number of Residues | 11 |
Details | BINDING SITE FOR RESIDUE SAL B 602 |
Chain | Residue |
B | LEU116 |
B | TYR120 |
B | ARG123 |
B | THR161 |
B | ILE217 |
B | THR324 |
B | GLY326 |
B | AMP601 |
B | HOH716 |
B | HOH1033 |
B | HOH1042 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 12 |
Details | BINDING: BINDING => ECO:0000269|PubMed:22628555, ECO:0007744|PDB:4EPM, ECO:0007744|PDB:4EQ4, ECO:0007744|PDB:4EQL |
Chain | Residue | Details |
A | SER95 | |
B | SER328 | |
B | TYR347 | |
B | ASP398 | |
A | THR301 | |
A | THR324 | |
A | SER328 | |
A | TYR347 | |
A | ASP398 | |
B | SER95 | |
B | THR301 | |
B | THR324 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000269|PubMed:22628555, ECO:0007744|PDB:4EQ4, ECO:0007744|PDB:4EQL |
Chain | Residue | Details |
A | TYR120 | |
B | TYR120 |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000269|PubMed:22628555, ECO:0007744|PDB:4EQ4 |
Chain | Residue | Details |
A | ARG417 | |
B | ARG417 |