4EO4
Crystal structure of the yeast mitochondrial threonyl-tRNA synthetase (MST1) in complex with seryl sulfamoyl adenylate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004829 | molecular_function | threonine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005759 | cellular_component | mitochondrial matrix |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006435 | biological_process | threonyl-tRNA aminoacylation |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0070159 | biological_process | mitochondrial threonyl-tRNA aminoacylation |
| A | 0140101 | molecular_function | catalytic activity, acting on a tRNA |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| B | 0004829 | molecular_function | threonine-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005759 | cellular_component | mitochondrial matrix |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0006435 | biological_process | threonyl-tRNA aminoacylation |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0070159 | biological_process | mitochondrial threonyl-tRNA aminoacylation |
| B | 0140101 | molecular_function | catalytic activity, acting on a tRNA |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| C | 0004829 | molecular_function | threonine-tRNA ligase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005739 | cellular_component | mitochondrion |
| C | 0005759 | cellular_component | mitochondrial matrix |
| C | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| C | 0006435 | biological_process | threonyl-tRNA aminoacylation |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0070159 | biological_process | mitochondrial threonyl-tRNA aminoacylation |
| C | 0140101 | molecular_function | catalytic activity, acting on a tRNA |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| D | 0004829 | molecular_function | threonine-tRNA ligase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005739 | cellular_component | mitochondrion |
| D | 0005759 | cellular_component | mitochondrial matrix |
| D | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| D | 0006435 | biological_process | threonyl-tRNA aminoacylation |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0070159 | biological_process | mitochondrial threonyl-tRNA aminoacylation |
| D | 0140101 | molecular_function | catalytic activity, acting on a tRNA |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE SSA A 1001 |
| Chain | Residue |
| A | MET131 |
| A | GLN287 |
| A | VAL288 |
| A | GLN292 |
| A | HIS319 |
| A | GLY324 |
| A | SER325 |
| A | ARG328 |
| A | ZN1003 |
| A | HOH1101 |
| A | ARG162 |
| A | GLU164 |
| A | THR173 |
| A | ARG174 |
| A | LEU175 |
| A | PHE178 |
| A | GLN180 |
| A | ASP182 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SSA A 1002 |
| Chain | Residue |
| A | VAL403 |
| A | GLY404 |
| A | ILE407 |
| A | LYS408 |
| A | ILE411 |
| A | ARG434 |
| A | ARG439 |
| A | HOH1217 |
| A | HOH1218 |
| A | HOH1219 |
| A | HOH1220 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 1003 |
| Chain | Residue |
| A | CYS133 |
| A | HIS184 |
| A | HIS319 |
| A | SSA1001 |
| site_id | AC4 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE SSA B 1001 |
| Chain | Residue |
| B | MET131 |
| B | CYS133 |
| B | ARG162 |
| B | GLU164 |
| B | THR173 |
| B | ARG174 |
| B | LEU175 |
| B | PHE178 |
| B | GLN180 |
| B | ASP182 |
| B | GLN287 |
| B | VAL288 |
| B | GLN292 |
| B | HIS319 |
| B | GLY324 |
| B | SER325 |
| B | ARG328 |
| B | ZN1003 |
| B | HOH1107 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE SSA B 1002 |
| Chain | Residue |
| B | VAL403 |
| B | GLY404 |
| B | LYS408 |
| B | ILE411 |
| B | ARG434 |
| B | ARG436 |
| B | ARG439 |
| B | HOH1192 |
| B | HOH1193 |
| B | HOH1194 |
| B | HOH1195 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 1003 |
| Chain | Residue |
| B | CYS133 |
| B | HIS184 |
| B | HIS319 |
| B | SSA1001 |
| site_id | AC7 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE SSA C 1001 |
| Chain | Residue |
| C | MET131 |
| C | ARG162 |
| C | GLU164 |
| C | THR173 |
| C | ARG174 |
| C | LEU175 |
| C | PHE178 |
| C | GLN180 |
| C | ASP182 |
| C | TYR270 |
| C | LYS273 |
| C | GLN287 |
| C | VAL288 |
| C | GLN292 |
| C | HIS319 |
| C | GLY324 |
| C | SER325 |
| C | ARG328 |
| C | ZN1003 |
| C | HOH1135 |
| C | HOH1137 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SSA C 1002 |
| Chain | Residue |
| B | LYS408 |
| B | HOH1195 |
| C | VAL403 |
| C | LYS408 |
| C | ILE411 |
| C | ARG434 |
| C | ARG439 |
| C | HOH1157 |
| C | HOH1165 |
| C | HOH1166 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 1003 |
| Chain | Residue |
| C | HIS184 |
| C | HIS319 |
| C | SSA1001 |
| C | CYS133 |
| site_id | BC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE SSA D 1001 |
| Chain | Residue |
| D | MET131 |
| D | CYS133 |
| D | ARG162 |
| D | GLU164 |
| D | THR173 |
| D | LEU175 |
| D | PHE178 |
| D | GLN180 |
| D | ASP182 |
| D | TYR270 |
| D | LYS273 |
| D | GLN287 |
| D | VAL288 |
| D | GLN292 |
| D | GLY324 |
| D | SER325 |
| D | ARG328 |
| D | ZN1003 |
| D | HOH1129 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SSA D 1002 |
| Chain | Residue |
| A | HOH1220 |
| D | VAL403 |
| D | LYS408 |
| D | ARG434 |
| D | ARG439 |
| D | HOH1156 |
| D | HOH1157 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 1003 |
| Chain | Residue |
| D | CYS133 |
| D | HIS184 |
| D | HIS319 |
| D | SSA1001 |
