4EME

X-ray crystal structure and specificity of the Plasmodium falciparum malaria aminopeptidase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004177	molecular_function	aminopeptidase activity
A	0005737	cellular_component	cytoplasm
A	0006508	biological_process	proteolysis
A	0008233	molecular_function	peptidase activity
A	0008237	molecular_function	metallopeptidase activity
A	0008270	molecular_function	zinc ion binding
A	0016787	molecular_function	hydrolase activity
A	0043171	biological_process	peptide catabolic process
A	0046872	molecular_function	metal ion binding
A	0070006	molecular_function	metalloaminopeptidase activity
B	0004177	molecular_function	aminopeptidase activity
B	0005737	cellular_component	cytoplasm
B	0006508	biological_process	proteolysis
B	0008233	molecular_function	peptidase activity
B	0008237	molecular_function	metallopeptidase activity
B	0008270	molecular_function	zinc ion binding
B	0016787	molecular_function	hydrolase activity
B	0043171	biological_process	peptide catabolic process
B	0046872	molecular_function	metal ion binding
B	0070006	molecular_function	metalloaminopeptidase activity
C	0004177	molecular_function	aminopeptidase activity
C	0005737	cellular_component	cytoplasm
C	0006508	biological_process	proteolysis
C	0008233	molecular_function	peptidase activity
C	0008237	molecular_function	metallopeptidase activity
C	0008270	molecular_function	zinc ion binding
C	0016787	molecular_function	hydrolase activity
C	0043171	biological_process	peptide catabolic process
C	0046872	molecular_function	metal ion binding
C	0070006	molecular_function	metalloaminopeptidase activity
D	0004177	molecular_function	aminopeptidase activity
D	0005737	cellular_component	cytoplasm
D	0006508	biological_process	proteolysis
D	0008233	molecular_function	peptidase activity
D	0008237	molecular_function	metallopeptidase activity
D	0008270	molecular_function	zinc ion binding
D	0016787	molecular_function	hydrolase activity
D	0043171	biological_process	peptide catabolic process
D	0046872	molecular_function	metal ion binding
D	0070006	molecular_function	metalloaminopeptidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 1001

Chain	Residue
A	HIS87
A	ASP325
A	GLU380
A	ASP435
A	ZN1002

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 1002

Chain	Residue
A	ASP325
A	GLU381
A	HIS535
A	ZN1001

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN B 1001

Chain	Residue
B	HIS87
B	ASP325
B	GLU380
B	ASP435
B	ZN1002

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN B 1002

Chain	Residue
B	ASP325
B	GLU380
B	GLU381
B	HIS535
B	ZN1001

---

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN C 1001

Chain	Residue
C	HIS87
C	ASP325
C	GLU380
C	ASP435
C	ZN1002

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 1002

Chain	Residue
C	ASP325
C	GLU381
C	HIS535
C	ZN1001

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN D 1001

Chain	Residue
D	HIS87
D	ASP325
D	GLU380
D	ASP435
D	ZN1002

---

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 1002

Chain	Residue
D	ASP325
D	GLU381
D	HIS535
D	ZN1001

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	20
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22709581","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4EME","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	20
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9ULA0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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