Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004713 | molecular_function | protein tyrosine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
| C | 0004672 | molecular_function | protein kinase activity |
| C | 0004713 | molecular_function | protein tyrosine kinase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006468 | biological_process | protein phosphorylation |
| D | 0004672 | molecular_function | protein kinase activity |
| D | 0004713 | molecular_function | protein tyrosine kinase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE JAK A 1201 |
| Chain | Residue |
| A | LEU881 |
| A | ASN1008 |
| A | LEU1010 |
| A | EDO1202 |
| A | HOH1304 |
| A | HOH1336 |
| A | VAL889 |
| A | ALA906 |
| A | GLU957 |
| A | PHE958 |
| A | LEU959 |
| A | GLY962 |
| A | GLU966 |
| A | ARG1007 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 1202 |
| Chain | Residue |
| A | ARG879 |
| A | PRO960 |
| A | GLY962 |
| A | JAK1201 |
| A | HOH1432 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 1203 |
| Chain | Residue |
| A | LEU977 |
| A | GLN980 |
| A | LEU1075 |
| A | TYR1077 |
| A | PRO1118 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 1204 |
| Chain | Residue |
| A | PRO867 |
| A | HIS869 |
| A | PHE870 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 1205 |
| Chain | Residue |
| A | LEU875 |
| A | GLU890 |
| A | LYS953 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 1206 |
| Chain | Residue |
| A | ASN976 |
| A | LYS978 |
| A | GLN979 |
| A | LYS982 |
| A | HOH1414 |
| site_id | AC7 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE JAK B 1201 |
| Chain | Residue |
| B | LEU881 |
| B | VAL889 |
| B | ALA906 |
| B | GLU957 |
| B | PHE958 |
| B | LEU959 |
| B | GLY962 |
| B | GLU966 |
| B | ARG1007 |
| B | ASN1008 |
| B | LEU1010 |
| B | HOH1314 |
| B | HOH1317 |
| B | HOH1424 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 1202 |
| Chain | Residue |
| B | GLU890 |
| B | VAL907 |
| B | LYS953 |
| B | HOH1329 |
| site_id | AC9 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE JAK C 1201 |
| Chain | Residue |
| C | LEU881 |
| C | VAL889 |
| C | ALA906 |
| C | GLU957 |
| C | PHE958 |
| C | LEU959 |
| C | GLY962 |
| C | GLU966 |
| C | ARG1007 |
| C | ASN1008 |
| C | LEU1010 |
| C | EDO1202 |
| C | HOH1302 |
| C | HOH1306 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO C 1202 |
| Chain | Residue |
| C | ARG879 |
| C | LEU881 |
| C | PRO960 |
| C | GLY962 |
| C | JAK1201 |
| C | HOH1448 |
| site_id | BC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO C 1203 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 1204 |
| Chain | Residue |
| C | LEU977 |
| C | GLN980 |
| C | LEU1075 |
| C | TYR1077 |
| C | HOH1375 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO C 1205 |
| Chain | Residue |
| C | ASP1040 |
| C | SER1043 |
| C | TYR1048 |
| C | CYS1052 |
| C | SER1056 |
| C | PHE1058 |
| D | MET1099 |
| site_id | BC5 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE JAK D 1201 |
| Chain | Residue |
| D | HOH1302 |
| D | HOH1306 |
| D | LEU881 |
| D | VAL889 |
| D | ALA906 |
| D | GLU957 |
| D | PHE958 |
| D | LEU959 |
| D | GLY962 |
| D | GLU966 |
| D | ARG1007 |
| D | ASN1008 |
| D | LEU1010 |
| D | GLY1020 |
| D | EDO1202 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO D 1202 |
| Chain | Residue |
| D | ARG879 |
| D | PRO960 |
| D | GLY962 |
| D | JAK1201 |
| D | HOH1386 |
| site_id | BC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO D 1203 |
| Chain | Residue |
| D | ASP866 |
| D | PRO969 |
| D | LYS970 |
| D | ASN971 |
| D | LYS972 |
| D | ASN973 |
| D | HOH1368 |
| D | HOH1392 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 28 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGHFGKVElCrydpegdntgeq......VAVK |
| Chain | Residue | Details |
| A | LEU881-LYS908 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. YVHrDLAARNVLV |
| Chain | Residue | Details |
| A | TYR999-VAL1011 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP1003 | |
| B | ASP1003 | |
| C | ASP1003 | |
| D | ASP1003 | |
| Chain | Residue | Details |
| A | LEU881 | |
| B | LEU881 | |
| C | LEU881 | |
| D | LEU881 | |
| Chain | Residue | Details |
| A | LYS908 | |
| B | LYS908 | |
| C | LYS908 | |
| D | LYS908 | |
| Chain | Residue | Details |
| A | PTR1034 | |
| A | PTR1035 | |
| B | PTR1034 | |
| B | PTR1035 | |
| C | PTR1034 | |
| C | PTR1035 | |
| D | PTR1034 | |
| D | PTR1035 | |
