4E57

Crystal Structure of spacer 6aa-shortened cephalosporin acylase mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016787	molecular_function	hydrolase activity
A	0016811	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
A	0017000	biological_process	antibiotic biosynthetic process
A	0046872	molecular_function	metal ion binding
B	0016787	molecular_function	hydrolase activity
B	0016811	molecular_function	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
B	0017000	biological_process	antibiotic biosynthetic process
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD A 701

Chain	Residue
A	ASP662

---

site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD A 702

Chain	Residue
A	ASP325

---

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD A 703

Chain	Residue
A	GLU161
A	THR192

---

site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD A 704

Chain	Residue
A	ASP506

---

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD A 705

Chain	Residue
A	ASP74

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD A 706

Chain	Residue
A	ASP123
A	HOH977
A	HOH1263

---

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD A 707

Chain	Residue
A	HIS650
A	GLU679

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD A 708

Chain	Residue
A	HIS465
A	HOH1471
A	HOH1472

---

site_id	AC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD A 709

Chain	Residue
A	ASP555

---

site_id	BC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD A 710

Chain	Residue
A	ASP577

---

site_id	BC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD A 711

Chain	Residue
A	ASP328

---

site_id	BC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD A 712

Chain	Residue
A	ARG264
A	GLU284

---

site_id	BC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD A 713

Chain	Residue
A	ASP425

---

site_id	BC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD A 714

Chain	Residue
A	GLU674

---

site_id	BC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD A 715

Chain	Residue
A	GLU316
A	ASP320
A	CD716

---

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD A 716

Chain	Residue
A	SER99
A	ASP101
A	GLU316
A	CD715

---

site_id	BC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD A 717

Chain	Residue
A	ASP329

---

site_id	BC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD A 718

Chain	Residue
A	GLU610

---

site_id	CC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD A 719

Chain	Residue
A	ASP451
A	ASP452

---

site_id	CC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD B 701

Chain	Residue
B	ASP123

---

site_id	CC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD B 702

Chain	Residue
B	ASP329

---

site_id	CC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD B 703

Chain	Residue
B	ASP74

---

site_id	CC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD B 704

Chain	Residue
B	HIS650
B	GLU679

---

site_id	CC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD B 705

Chain	Residue
B	HIS465
B	HOH1430
B	HOH1432

---

site_id	CC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD B 706

Chain	Residue
B	ASP555

---

site_id	CC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CD B 707

Chain	Residue
B	ASP577
B	HOH1286

---

site_id	CC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD B 708

Chain	Residue
B	ASP328

---

site_id	DC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD B 709

Chain	Residue
B	ASP662

---

site_id	DC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD B 710

Chain	Residue
B	GLU674

---

site_id	DC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD B 711

Chain	Residue
B	ASP425

---

site_id	DC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CD B 712

Chain	Residue
B	GLU316
B	ASP320
B	CD713

---

site_id	DC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CD B 713

Chain	Residue
B	SER99
B	ASP101
B	GLU316
B	CD712

---

site_id	DC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CD B 714

Chain	Residue
B	GLU610

---