4E0X
Crystal structure of the kainate receptor GluK1 ligand-binding domain in complex with kainate in the absence of glycerol
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE KAI A 301 |
| Chain | Residue |
| A | GLU13 |
| A | SER173 |
| A | GLU190 |
| A | HOH404 |
| A | HOH406 |
| A | HOH413 |
| A | TYR61 |
| A | PRO88 |
| A | LEU89 |
| A | THR90 |
| A | ARG95 |
| A | GLY140 |
| A | SER141 |
| A | THR142 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 302 |
| Chain | Residue |
| A | ARG20 |
| A | SER22 |
| B | LYS147 |
| B | TRP158 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 303 |
| Chain | Residue |
| A | ARG31 |
| A | HOH474 |
| A | HOH563 |
| A | HOH607 |
| A | HOH619 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 305 |
| Chain | Residue |
| A | LYS103 |
| A | HOH500 |
| B | LYS103 |
| B | HOH483 |
| site_id | AC5 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE KAI B 301 |
| Chain | Residue |
| B | GLU13 |
| B | TYR61 |
| B | PRO88 |
| B | THR90 |
| B | ARG95 |
| B | GLY140 |
| B | SER141 |
| B | THR142 |
| B | GLU190 |
| B | HOH405 |
| B | HOH408 |
| B | HOH416 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 302 |
| Chain | Residue |
| A | GLN165 |
| A | HOH598 |
| B | ARG20 |
| B | SER22 |
| B | LYS24 |
| B | HOH615 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 B 303 |
| Chain | Residue |
| A | HOH468 |
| B | ARG31 |
| B | VAL53 |
| B | LYS54 |
| B | HOH472 |
| B | HOH504 |
| B | HOH596 |
| B | HOH634 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 304 |
| Chain | Residue |
| A | LYS116 |
| B | ARG4 |
| B | HIS80 |
| B | PRO225 |
| B | HOH559 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 305 |
| Chain | Residue |
| A | LYS60 |
| A | LYS171 |
| B | LYS171 |
| B | HOH629 |
| site_id | BC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 306 |
| Chain | Residue |
| B | ARG164 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15710405","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1YCJ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15710405","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15721240","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1YCJ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine; by PKC","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine; by PKC","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
