4DQI
Ternary complex of Bacillus DNA Polymerase I Large Fragment, DNA duplex, and dCTP (paired with dG of template)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| A | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| A | 0006260 | biological_process | DNA replication |
| A | 0006261 | biological_process | DNA-templated DNA replication |
| A | 0008408 | molecular_function | 3'-5' exonuclease activity |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003887 | molecular_function | DNA-directed DNA polymerase activity |
| D | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| D | 0006260 | biological_process | DNA replication |
| D | 0006261 | biological_process | DNA-templated DNA replication |
| D | 0008408 | molecular_function | 3'-5' exonuclease activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 901 |
| Chain | Residue |
| A | ASP653 |
| A | TYR654 |
| A | ASP830 |
| A | DCP902 |
| site_id | AC2 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE DCP A 902 |
| Chain | Residue |
| A | ILE657 |
| A | GLU658 |
| A | HIS682 |
| A | ARG702 |
| A | LYS706 |
| A | PHE710 |
| A | ASP830 |
| A | MG901 |
| A | HOH1003 |
| A | HOH1027 |
| A | HOH1108 |
| A | HOH1241 |
| A | HOH1273 |
| A | HOH1279 |
| A | HOH1482 |
| B | DOC29 |
| B | HOH121 |
| C | DG3 |
| C | DG4 |
| A | ARG615 |
| A | ASP653 |
| A | TYR654 |
| A | SER655 |
| A | GLN656 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DCP A 903 |
| Chain | Residue |
| A | GLU469 |
| A | GLN470 |
| A | ASP471 |
| A | ARG472 |
| A | LEU473 |
| A | LEU767 |
| A | HIS768 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 904 |
| Chain | Residue |
| A | ARG517 |
| A | ASN573 |
| A | HOH1558 |
| D | LYS730 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG D 901 |
| Chain | Residue |
| D | TYR654 |
| D | ASP830 |
| D | DCP902 |
| D | HOH1741 |
| site_id | AC6 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE DCP D 902 |
| Chain | Residue |
| D | ARG615 |
| D | TYR654 |
| D | GLN656 |
| D | ILE657 |
| D | GLU658 |
| D | HIS682 |
| D | ARG702 |
| D | LYS706 |
| D | PHE710 |
| D | ASP830 |
| D | MG901 |
| D | HOH1018 |
| D | HOH1124 |
| D | HOH1137 |
| D | HOH1324 |
| D | HOH1389 |
| D | HOH1741 |
| E | DOC29 |
| F | DG3 |
| F | DG4 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 D 903 |
| Chain | Residue |
| D | MET299 |
| D | ALA300 |
| D | ARG343 |
| D | ARG677 |
Functional Information from PROSITE/UniProt
| site_id | PS00447 |
| Number of Residues | 20 |
| Details | DNA_POLYMERASE_A DNA polymerase family A signature. RrqAKavnFGivYgiSdygL |
| Chain | Residue | Details |
| A | ARG702-LEU721 |
