4DPX
Crystal structure of S192A Staphylococcus epidermidis mevalonate diphosphate decarboxylase
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004163 | molecular_function | diphosphomevalonate decarboxylase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0008299 | biological_process | isoprenoid biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| A | 0019287 | biological_process | isopentenyl diphosphate biosynthetic process, mevalonate pathway |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004163 | molecular_function | diphosphomevalonate decarboxylase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0008299 | biological_process | isoprenoid biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0019287 | biological_process | isopentenyl diphosphate biosynthetic process, mevalonate pathway |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 401 |
| Chain | Residue |
| A | VAL98 |
| A | PRO99 |
| A | THR100 |
| A | ALA101 |
| A | HOH598 |
| B | PRO99 |
| B | THR100 |
| B | HOH538 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 402 |
| Chain | Residue |
| A | SER141 |
| A | ALA192 |
| A | MET196 |
| A | ALA284 |
| A | HOH514 |
| A | HOH562 |
| A | HOH570 |
| A | HOH642 |
| A | HOH683 |
| A | TYR18 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FMT A 403 |
| Chain | Residue |
| A | ILE13 |
| A | LEU104 |
| A | ALA105 |
| A | ASP283 |
| A | LYS289 |
| A | HOH526 |
| A | HOH542 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FMT A 404 |
| Chain | Residue |
| A | TYR18 |
| A | LYS21 |
| A | ILE27 |
| A | GLY140 |
| A | ARG193 |
| A | HOH642 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 401 |
| Chain | Residue |
| A | ASN184 |
| A | LYS312 |
| A | HOH634 |
| B | ASN184 |
| B | ASN185 |
| B | SER187 |
| B | HOH610 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FMT B 402 |
| Chain | Residue |
| B | TYR18 |
| B | SER141 |
| B | HOH524 |
| B | HOH564 |
| B | HOH660 |
| B | HOH675 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT B 403 |
| Chain | Residue |
| B | ASN12 |
| B | SER141 |
| B | ARG144 |
| B | HOH515 |
| B | HOH716 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FMT B 404 |
| Chain | Residue |
| B | THR11 |
| B | ALA105 |
| B | SER106 |
| B | SER107 |
| B | ALA108 |
| B | SER109 |
| B | HOH697 |
