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4DKX

Crystal Structure of the Rab 6A'(Q72L)

Functional Information from GO Data
ChainGOidnamespacecontents
A0000139cellular_componentGolgi membrane
A0002080cellular_componentacrosomal membrane
A0003924molecular_functionGTPase activity
A0005515molecular_functionprotein binding
A0005525molecular_functionGTP binding
A0005789cellular_componentendoplasmic reticulum membrane
A0005794cellular_componentGolgi apparatus
A0005802cellular_componenttrans-Golgi network
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006886biological_processintracellular protein transport
A0006890biological_processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
A0006891biological_processintra-Golgi vesicle-mediated transport
A0012505cellular_componentendomembrane system
A0015031biological_processprotein transport
A0016020cellular_componentmembrane
A0016192biological_processvesicle-mediated transport
A0018125biological_processpeptidyl-cysteine methylation
A0019882biological_processantigen processing and presentation
A0019904molecular_functionprotein domain specific binding
A0030667cellular_componentsecretory granule membrane
A0031175biological_processneuron projection development
A0031410cellular_componentcytoplasmic vesicle
A0031489molecular_functionmyosin V binding
A0032588cellular_componenttrans-Golgi network membrane
A0034067biological_processprotein localization to Golgi apparatus
A0034498biological_processearly endosome to Golgi transport
A0042147biological_processretrograde transport, endosome to Golgi
A0070062cellular_componentextracellular exosome
A0070381cellular_componentendosome to plasma membrane transport vesicle
A0072385biological_processminus-end-directed organelle transport along microtubule
A1903292biological_processprotein localization to Golgi membrane
B0000139cellular_componentGolgi membrane
B0002080cellular_componentacrosomal membrane
B0003924molecular_functionGTPase activity
B0005515molecular_functionprotein binding
B0005525molecular_functionGTP binding
B0005789cellular_componentendoplasmic reticulum membrane
B0005794cellular_componentGolgi apparatus
B0005802cellular_componenttrans-Golgi network
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0006886biological_processintracellular protein transport
B0006890biological_processretrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
B0006891biological_processintra-Golgi vesicle-mediated transport
B0012505cellular_componentendomembrane system
B0015031biological_processprotein transport
B0016020cellular_componentmembrane
B0016192biological_processvesicle-mediated transport
B0018125biological_processpeptidyl-cysteine methylation
B0019882biological_processantigen processing and presentation
B0019904molecular_functionprotein domain specific binding
B0030667cellular_componentsecretory granule membrane
B0031175biological_processneuron projection development
B0031410cellular_componentcytoplasmic vesicle
B0031489molecular_functionmyosin V binding
B0032588cellular_componenttrans-Golgi network membrane
B0034067biological_processprotein localization to Golgi apparatus
B0034498biological_processearly endosome to Golgi transport
B0042147biological_processretrograde transport, endosome to Golgi
B0070062cellular_componentextracellular exosome
B0070381cellular_componentendosome to plasma membrane transport vesicle
B0072385biological_processminus-end-directed organelle transport along microtubule
B1903292biological_processprotein localization to Golgi membrane
Functional Information from PDB Data
site_idAC1
Number of Residues19
DetailsBINDING SITE FOR RESIDUE GDP A 301
ChainResidue
ASER23
ALYS127
AASP129
ALEU130
ASER156
AALA157
ALYS158
AMG302
AHOH454
AHOH518
AHOH519
AVAL24
AGLY25
ALYS26
ATHR27
ASER28
APHE38
AASP39
AASN126

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG A 302
ChainResidue
ATHR27
AGDP301
AHOH518
AHOH519
AHOH520

site_idAC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE MG B 301
ChainResidue
BTHR27
BGDP302
BHOH525
BHOH526
BHOH527

site_idAC4
Number of Residues19
DetailsBINDING SITE FOR RESIDUE GDP B 302
ChainResidue
BSER23
BVAL24
BGLY25
BLYS26
BTHR27
BSER28
BPHE38
BASN126
BLYS127
BASP129
BLEU130
BSER156
BALA157
BLYS158
BMG301
BHOH410
BHOH480
BHOH525
BHOH526

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsBINDING: BINDING => ECO:0000269|PubMed:16332443, ECO:0000269|PubMed:18243103, ECO:0000269|PubMed:19141279
ChainResidueDetails
AGLY20
AASP68
AASN126
ASER156
BGLY20
BASP68
BASN126
BSER156

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: N-acetylserine => ECO:0000269|Ref.12, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:22814378, ECO:0007744|PubMed:25944712
ChainResidueDetails
ASER2
BSER2

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: O-AMP-tyrosine; by Legionella DrrA => ECO:0000269|PubMed:21822290
ChainResidueDetails
ATYR82
BTYR82

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P35279
ChainResidueDetails
ASER184
BSER184

site_idSWS_FT_FI5
Number of Residues2
DetailsMOD_RES: Cysteine methyl ester => ECO:0000250
ChainResidueDetails
ACYS208
BCYS208

site_idSWS_FT_FI6
Number of Residues4
DetailsLIPID: S-geranylgeranyl cysteine => ECO:0000250
ChainResidueDetails
ACYS206
ACYS208
BCYS206
BCYS208

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PDB entries from 2024-05-15

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