Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4DIB

The crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Bacillus anthracis str. Sterne

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0002020	molecular_function	protease binding
A	0005829	cellular_component	cytosol
A	0005975	biological_process	carbohydrate metabolic process
A	0006006	biological_process	glucose metabolic process
A	0016020	cellular_component	membrane
A	0016491	molecular_function	oxidoreductase activity
A	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
A	0030554	molecular_function	adenyl nucleotide binding
A	0044281	biological_process	small molecule metabolic process
A	0047100	molecular_function	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity
A	0050661	molecular_function	NADP binding
A	0051287	molecular_function	NAD binding
B	0000166	molecular_function	nucleotide binding
B	0002020	molecular_function	protease binding
B	0005829	cellular_component	cytosol
B	0005975	biological_process	carbohydrate metabolic process
B	0006006	biological_process	glucose metabolic process
B	0016020	cellular_component	membrane
B	0016491	molecular_function	oxidoreductase activity
B	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
B	0030554	molecular_function	adenyl nucleotide binding
B	0044281	biological_process	small molecule metabolic process
B	0047100	molecular_function	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity
B	0050661	molecular_function	NADP binding
B	0051287	molecular_function	NAD binding
C	0000166	molecular_function	nucleotide binding
C	0002020	molecular_function	protease binding
C	0005829	cellular_component	cytosol
C	0005975	biological_process	carbohydrate metabolic process
C	0006006	biological_process	glucose metabolic process
C	0016020	cellular_component	membrane
C	0016491	molecular_function	oxidoreductase activity
C	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
C	0030554	molecular_function	adenyl nucleotide binding
C	0044281	biological_process	small molecule metabolic process
C	0047100	molecular_function	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity
C	0050661	molecular_function	NADP binding
C	0051287	molecular_function	NAD binding
D	0000166	molecular_function	nucleotide binding
D	0002020	molecular_function	protease binding
D	0005829	cellular_component	cytosol
D	0005975	biological_process	carbohydrate metabolic process
D	0006006	biological_process	glucose metabolic process
D	0016020	cellular_component	membrane
D	0016491	molecular_function	oxidoreductase activity
D	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
D	0030554	molecular_function	adenyl nucleotide binding
D	0044281	biological_process	small molecule metabolic process
D	0047100	molecular_function	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity
D	0050661	molecular_function	NADP binding
D	0051287	molecular_function	NAD binding
E	0000166	molecular_function	nucleotide binding
E	0002020	molecular_function	protease binding
E	0005829	cellular_component	cytosol
E	0005975	biological_process	carbohydrate metabolic process
E	0006006	biological_process	glucose metabolic process
E	0016020	cellular_component	membrane
E	0016491	molecular_function	oxidoreductase activity
E	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
E	0030554	molecular_function	adenyl nucleotide binding
E	0044281	biological_process	small molecule metabolic process
E	0047100	molecular_function	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity
E	0050661	molecular_function	NADP binding
E	0051287	molecular_function	NAD binding
F	0000166	molecular_function	nucleotide binding
F	0002020	molecular_function	protease binding
F	0005829	cellular_component	cytosol
F	0005975	biological_process	carbohydrate metabolic process
F	0006006	biological_process	glucose metabolic process
F	0016020	cellular_component	membrane
F	0016491	molecular_function	oxidoreductase activity
F	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
F	0030554	molecular_function	adenyl nucleotide binding
F	0044281	biological_process	small molecule metabolic process
F	0047100	molecular_function	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity
F	0050661	molecular_function	NADP binding
F	0051287	molecular_function	NAD binding
G	0000166	molecular_function	nucleotide binding
G	0002020	molecular_function	protease binding
G	0005829	cellular_component	cytosol
G	0005975	biological_process	carbohydrate metabolic process
G	0006006	biological_process	glucose metabolic process
G	0016020	cellular_component	membrane
G	0016491	molecular_function	oxidoreductase activity
G	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
G	0030554	molecular_function	adenyl nucleotide binding
G	0044281	biological_process	small molecule metabolic process
G	0047100	molecular_function	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity
G	0050661	molecular_function	NADP binding
G	0051287	molecular_function	NAD binding
H	0000166	molecular_function	nucleotide binding
H	0002020	molecular_function	protease binding
H	0005829	cellular_component	cytosol
H	0005975	biological_process	carbohydrate metabolic process
H	0006006	biological_process	glucose metabolic process
H	0016020	cellular_component	membrane
H	0016491	molecular_function	oxidoreductase activity
H	0016620	molecular_function	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
H	0030554	molecular_function	adenyl nucleotide binding
H	0044281	biological_process	small molecule metabolic process
H	0047100	molecular_function	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity
H	0050661	molecular_function	NADP binding
H	0051287	molecular_function	NAD binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 401

Chain	Residue
A	VAL133
A	ASN134
A	GLU135
A	ASP136

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 C 401

Chain	Residue
C	ALA211
C	SER150
C	THR152
C	HIS178
C	THR209
C	GLY210

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 D 401

Chain	Residue
D	SER150
D	THR152
D	HIS178
D	THR209
D	GLY210
D	ALA211

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 E 401

Chain	Residue
E	SER150
E	THR152
E	HIS178
E	THR209
E	GLY210
E	ALA211
E	HOH513

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 F 401

Chain	Residue
F	SER150
F	THR152
F	THR209
F	GLY210
F	ALA211
F	HOH519

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 H 401

Chain	Residue
H	SER150
H	THR152
H	THR209
H	GLY210
H	ALA211
H	HOH523

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 H 402

Chain	Residue
C	ARG198
C	ALA199
H	ARG11
H	ARG14
H	ASP47
H	THR48

Functional Information from PROSITE/UniProt

site_id	PS00071
Number of Residues	8
Details	GAPDH Glyceraldehyde 3-phosphate dehydrogenase active site. ASCTTNcL

Chain	Residue	Details
A	ALA149-LEU156

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)