4D5G
Structure of recombinant CDH-H28AN484A
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003984 | molecular_function | acetolactate synthase activity |
| A | 0005948 | cellular_component | acetolactate synthase complex |
| A | 0009097 | biological_process | isoleucine biosynthetic process |
| A | 0009099 | biological_process | valine biosynthetic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0019752 | biological_process | carboxylic acid metabolic process |
| A | 0030976 | molecular_function | thiamine pyrophosphate binding |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003984 | molecular_function | acetolactate synthase activity |
| B | 0005948 | cellular_component | acetolactate synthase complex |
| B | 0009097 | biological_process | isoleucine biosynthetic process |
| B | 0009099 | biological_process | valine biosynthetic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0019752 | biological_process | carboxylic acid metabolic process |
| B | 0030976 | molecular_function | thiamine pyrophosphate binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 38 |
| Details | BINDING SITE FOR RESIDUE FAD A 1588 |
| Chain | Residue |
| A | HIS153 |
| A | ALA257 |
| A | GLY258 |
| A | PHE259 |
| A | CYS260 |
| A | GLY261 |
| A | GLY279 |
| A | SER280 |
| A | ARG281 |
| A | LEU282 |
| A | SER283 |
| A | GLY213 |
| A | TRP285 |
| A | GLY286 |
| A | ASP302 |
| A | THR303 |
| A | ASP304 |
| A | ALA320 |
| A | ASP321 |
| A | ALA322 |
| A | SER420 |
| A | MET421 |
| A | GLY214 |
| A | ALA422 |
| A | GLY424 |
| A | HOH2062 |
| A | HOH2115 |
| A | HOH2199 |
| A | HOH2200 |
| A | HOH2201 |
| A | HOH2214 |
| A | HOH2268 |
| A | GLY215 |
| A | ARG218 |
| A | SER219 |
| A | THR239 |
| A | SER240 |
| A | THR241 |
| site_id | AC2 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE TPP A 1589 |
| Chain | Residue |
| A | ILE398 |
| A | GLY399 |
| A | ASN400 |
| A | HIS401 |
| A | GLY424 |
| A | LEU426 |
| A | GLY450 |
| A | ASP451 |
| A | GLY452 |
| A | ALA453 |
| A | TYR456 |
| A | ASN478 |
| A | SER480 |
| A | TYR481 |
| A | GLY482 |
| A | ALA483 |
| A | ASN484 |
| A | MG1590 |
| A | HOH2279 |
| A | HOH2294 |
| A | HOH2356 |
| B | ILE26 |
| B | GLU52 |
| B | HIS76 |
| B | VAL78 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 1590 |
| Chain | Residue |
| A | ASP451 |
| A | ASN478 |
| A | SER480 |
| A | TPP1589 |
| A | HOH2279 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PG4 A 1591 |
| Chain | Residue |
| A | PRO441 |
| A | ARG444 |
| A | PRO470 |
| A | SER546 |
| A | GLN549 |
| A | ASP554 |
| A | PG41594 |
| A | HOH2244 |
| A | HOH2278 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE 1PG A 1592 |
| Chain | Residue |
| A | SER369 |
| A | GLY513 |
| A | ALA514 |
| A | LYS537 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PG4 A 1593 |
| Chain | Residue |
| A | GLU368 |
| A | ARG379 |
| A | ALA382 |
| A | ARG385 |
| A | LYS386 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PG4 A 1594 |
| Chain | Residue |
| A | GLN367 |
| A | ILE533 |
| A | ASP534 |
| A | GLY536 |
| A | PG41591 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE PG4 A 1595 |
| Chain | Residue |
| A | GLU134 |
| A | ARG135 |
| A | HOH2125 |
| B | GLU134 |
| B | ARG135 |
| B | HOH2056 |
| B | HOH2068 |
| B | HOH2225 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG A 1596 |
| Chain | Residue |
| A | ARG91 |
| A | THR124 |
| A | PRO125 |
| A | ALA127 |
| A | ARG128 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG A 1597 |
| Chain | Residue |
| A | LYS66 |
| A | ARG218 |
| A | GLY220 |
| A | GLN494 |
| A | HOH2158 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PG4 A 1598 |
| Chain | Residue |
| A | GLU15 |
| A | HIS41 |
| A | GLU499 |
| A | MG1600 |
| A | HOH2359 |
| B | GLU466 |
| site_id | BC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PG4 A 1599 |
| Chain | Residue |
| A | GLN117 |
| A | VAL118 |
| A | TRP120 |
| A | ARG132 |
| A | HOH2071 |
| B | HOH2051 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG A 1600 |
| Chain | Residue |
| A | PG41598 |
| A | HOH2009 |
| A | HOH2359 |
| site_id | BC5 |
| Number of Residues | 38 |
| Details | BINDING SITE FOR RESIDUE FAD B 1589 |
| Chain | Residue |
| B | HIS153 |
| B | GLY213 |
| B | GLY214 |
| B | GLY215 |
| B | ARG218 |
| B | SER219 |
| B | THR239 |
| B | SER240 |
| B | THR241 |
| B | ALA257 |
| B | GLY258 |
| B | PHE259 |
| B | CYS260 |
| B | GLY261 |
| B | GLY279 |
| B | SER280 |
| B | ARG281 |
| B | LEU282 |
| B | SER283 |
| B | TRP285 |
| B | GLY286 |
| B | ASP302 |
| B | THR303 |
| B | ASP304 |
| B | ALA320 |
| B | ASP321 |
| B | ALA322 |
| B | SER420 |
| B | MET421 |
| B | ALA422 |
| B | GLY424 |
| B | HOH2033 |
| B | HOH2063 |
| B | HOH2117 |
| B | HOH2118 |
| B | HOH2119 |
| B | HOH2129 |
| B | HOH2169 |
| site_id | BC6 |
| Number of Residues | 26 |
| Details | BINDING SITE FOR RESIDUE TPP B 1590 |
| Chain | Residue |
| A | ILE26 |
| A | GLY27 |
| A | GLU52 |
| A | HIS76 |
| A | VAL78 |
| A | GLN116 |
| B | ILE398 |
| B | GLY399 |
| B | ASN400 |
| B | HIS401 |
| B | GLY424 |
| B | LEU426 |
| B | GLY450 |
| B | ASP451 |
| B | GLY452 |
| B | ALA453 |
| B | TYR456 |
| B | ASN478 |
| B | SER480 |
| B | TYR481 |
| B | GLY482 |
| B | ALA483 |
| B | ASN484 |
| B | MG1591 |
| B | HOH2179 |
| B | HOH2185 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 1591 |
| Chain | Residue |
| B | ASP451 |
| B | ASN478 |
| B | SER480 |
| B | TPP1590 |
| B | HOH2179 |
| site_id | BC8 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2PE B 1592 |
| Chain | Residue |
| B | VAL387 |
| B | ARG389 |
| B | PRO441 |
| B | ASN442 |
| B | SER443 |
| B | ARG444 |
| B | PRO470 |
| B | HOH2236 |
| site_id | BC9 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE 2PE B 1593 |
| Chain | Residue |
| B | GLU151 |
| B | GLU151 |
| B | HIS153 |
| B | ALA184 |
| B | ALA184 |
| B | LYS185 |
| B | LEU188 |
| B | THR303 |
| B | THR303 |
| B | PRO305 |
| B | PG41594 |
| B | PG41594 |
| B | HOH2237 |
| site_id | CC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PG4 B 1594 |
| Chain | Residue |
| B | ARG148 |
| B | ARG183 |
| B | ALA184 |
| B | LEU308 |
| B | 2PE1593 |
| B | 2PE1593 |
| B | HOH2074 |
| site_id | CC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PG4 B 1595 |
| Chain | Residue |
| B | ARG91 |
| B | THR124 |
| B | ALA127 |
| B | ARG128 |
| site_id | CC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE PEG B 1596 |
| Chain | Residue |
| B | GLN549 |
| site_id | CC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE PG4 B 1597 |
| Chain | Residue |
| A | ARG132 |
| A | GLU134 |
| A | HOH2096 |
| A | HOH2101 |
| B | ALA109 |
| B | VAL118 |
| B | TRP120 |
| B | ARG132 |
| B | HOH2040 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | GLU52 | |
| A | ASP451 | |
| A | ASN478 | |
| B | GLU52 | |
| B | ASP451 | |
| B | ASN478 |
