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4CVZ

COMPLEX OF A B21 CHICKEN MHC CLASS I MOLECULE AND A 10MER CHICKEN PEPTIDE

Functional Information from GO Data
ChainGOidnamespacecontents
B0002474biological_processantigen processing and presentation of peptide antigen via MHC class I
B0002502biological_processpeptide antigen assembly with MHC class I protein complex
B0002503biological_processpeptide antigen assembly with MHC class II protein complex
B0002726biological_processpositive regulation of T cell cytokine production
B0005198molecular_functionstructural molecule activity
B0005576cellular_componentextracellular region
B0005765cellular_componentlysosomal membrane
B0005794cellular_componentGolgi apparatus
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0006879biological_processintracellular iron ion homeostasis
B0006955biological_processimmune response
B0007611biological_processlearning or memory
B0019885biological_processantigen processing and presentation of endogenous peptide antigen via MHC class I
B0019886biological_processantigen processing and presentation of exogenous peptide antigen via MHC class II
B0023026molecular_functionMHC class II protein complex binding
B0031902cellular_componentlate endosome membrane
B0034756biological_processregulation of iron ion transport
B0042605molecular_functionpeptide antigen binding
B0042612cellular_componentMHC class I protein complex
B0042613cellular_componentMHC class II protein complex
B0042802molecular_functionidentical protein binding
B0042803molecular_functionprotein homodimerization activity
B0042824cellular_componentMHC class I peptide loading complex
B0048260biological_processpositive regulation of receptor-mediated endocytosis
B0050680biological_processnegative regulation of epithelial cell proliferation
B0050768biological_processnegative regulation of neurogenesis
B0050778biological_processpositive regulation of immune response
B0050870biological_processpositive regulation of T cell activation
B0051289biological_processprotein homotetramerization
B0071281biological_processcellular response to iron ion
B0071316biological_processcellular response to nicotine
B1990000biological_processamyloid fibril formation
B1990712cellular_componentHFE-transferrin receptor complex
B2000774biological_processpositive regulation of cellular senescence
B2000978biological_processnegative regulation of forebrain neuron differentiation
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE EDO B 1099
ChainResidue
BASN56
BASP57
BHOH2010
BHOH2015

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO B 1100
ChainResidue
AMET96
BASN56
BASP57
BTRP59
BHOH2010

site_idAC3
Number of Residues3
DetailsBINDING SITE FOR RESIDUE EDO B 1101
ChainResidue
BASN56
BGLN62
BEDO1102

site_idAC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO B 1102
ChainResidue
BSER54
BPHE55
BGLN62
BEDO1101
BHOH2016

site_idAC5
Number of Residues8
DetailsBINDING SITE FOR RESIDUE EDO A 1279
ChainResidue
AMET12
APRO15
ALEU19
APRO20
AVAL23
AHOH2023
AHOH2024
BARG63

site_idAC6
Number of Residues4
DetailsBINDING SITE FOR RESIDUE EDO A 1280
ChainResidue
AASP234
AHOH2025
BARG11
BHIS66

Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACKVEH
ChainResidueDetails
BTYR77-HIS83
ATYR253-HIS259

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PDB entries from 2024-08-07

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