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Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4CU8

Unravelling the multiple functions of the architecturally intricate Streptococcus pneumoniae beta-galactosidase, BgaA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0005975	biological_process	carbohydrate metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	BINDING SITE FOR RESIDUE DGJ A 1985

Chain	Residue
A	ARG288
A	GLU716
A	PHE733
A	EDO2021
A	HOH3277
A	HIS484
A	ASN563
A	GLU564
A	TYR624
A	GLU645
A	SER648
A	TRP685
A	TRP708

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 1986

Chain	Residue
A	ILE316
A	PHE422
A	GLY423
A	ARG425
A	ASN552
A	PRO554

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1987

Chain	Residue
A	TYR426
A	TYR427
A	THR591
A	HOH3146

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 1988

Chain	Residue
A	TRP693
A	GLN752
A	TYR822
A	GLN823
A	HOH3451
A	HOH3476
A	HOH3524

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 1989

Chain	Residue
A	TYR237
A	ASN254
A	GLY255
A	TYR519
A	EDO2007
A	HOH3118
A	HOH3315

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 1990

Chain	Residue
A	ALA568
A	HIS610
A	ALA614
A	HOH3338
A	HOH3356

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE EDO A 1991

Chain	Residue
A	ASN667
A	GLY668
A	PRO669
A	TYR673
A	TRP720
A	THR726
A	HOH3424

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 1992

Chain	Residue
A	LYS590
A	THR591

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 1993

Chain	Residue
A	ASN396
A	ASP397
A	HOH3216

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 1994

Chain	Residue
A	LYS419
A	HOH3229

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1995

Chain	Residue
A	GLU489
A	LEU492
A	ASN553
A	HOH3301

site_id	BC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 1996

Chain	Residue
A	ASN165
A	SER166

site_id	BC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 1997

Chain	Residue
A	GLY512
A	LYS515
A	PRO516

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 1998

Chain	Residue
A	ARG653
A	ASP677
A	PRO742
A	LYS743
A	HIS744

site_id	BC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE EDO A 1999

Chain	Residue
A	TYR159

site_id	BC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 2000

Chain	Residue
A	GLU310
A	LYS311
A	GLU531
A	ARG544

site_id	BC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 2001

Chain	Residue
A	HIS332
A	VAL333
A	THR334
A	ASP381
A	ALA382

site_id	BC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 2002

Chain	Residue
A	THR378
A	SER379

site_id	CC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 2003

Chain	Residue
A	GLN471
A	GLU474
A	PRO742
A	HOH3474

site_id	CC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 2004

Chain	Residue
A	TYR462
A	GLU489
A	GLN490
A	GLN493
A	HOH3072
A	HOH3304

site_id	CC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 2005

Chain	Residue
A	LYS537
A	ASN802
A	GLN840
A	HOH3516

site_id	CC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 2006

Chain	Residue
A	ASN772
A	GLU774

site_id	CC5
Number of Residues	10
Details	BINDING SITE FOR RESIDUE EDO A 2007

Chain	Residue
A	GLY255
A	TYR256
A	HIS484
A	ASN485
A	ALA506
A	PHE507
A	ASP508
A	EDO1989
A	HOH3306
A	ASN254

site_id	CC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 2008

Chain	Residue
A	LYS586
A	LYS590

site_id	CC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 2009

Chain	Residue
A	LEU395
A	ILE442
A	ASN478
A	HOH3214
A	HOH3272
A	HOH3300

site_id	CC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 2010

Chain	Residue
A	ARG661
A	SER666
A	HOH3407
A	HOH3415

site_id	CC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE EDO A 2011

Chain	Residue
A	LEU808

site_id	DC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 2012

Chain	Residue
A	LYS972
A	SER973

site_id	DC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 2014

Chain	Residue
A	GLY566
A	ASN569

site_id	DC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 2015

Chain	Residue
A	GLY609
A	LYS773

site_id	DC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE EDO A 2016

Chain	Residue
A	GLN815

site_id	DC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 2017

Chain	Residue
A	ASN208
A	HOH3056
A	HOH3639
A	HOH3640

site_id	DC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 2018

Chain	Residue
A	VAL152
A	ASP153

site_id	DC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE EDO A 2019

Chain	Residue
A	LYS612

site_id	DC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE EDO A 2020

Chain	Residue
A	ARG858

site_id	DC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 2021

Chain	Residue
A	GLU564
A	ASP599
A	ARG602
A	TYR624
A	TRP685
A	DGJ1985

site_id	EC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 2022

Chain	Residue
A	GLY865
A	LYS866

site_id	EC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 2023

Chain	Residue
A	HIS913
A	GLY914

site_id	EC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 2024

Chain	Residue
A	ARG602
A	HOH3441

site_id	EC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 2025

Chain	Residue
A	ASN724
A	HOH3463

site_id	EC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 2026

Chain	Residue
A	GLU892
A	LYS948
A	HOH3296

site_id	EC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 2027

Chain	Residue
A	LYS343
A	HIS345

site_id	EC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 2028

Chain	Residue
A	ASP850
A	GLU851
A	HOH3513

site_id	EC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE EDO A 2029

Chain	Residue
A	ARG849

site_id	EC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 2030

Chain	Residue
A	GLN201
A	LYS515
A	ASN722

site_id	FC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 2031

Chain	Residue
A	LYS809
A	LYS836
A	HOH3518

site_id	FC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 2032

Chain	Residue
A	ASP526
A	HOH3322

site_id	FC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO A 2033

Chain	Residue
A	ARG533
A	LYS534

site_id	FC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 2034

Chain	Residue
A	SER928
A	ARG929
A	LYS943
A	HOH3604
A	HOH3643

site_id	FC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 2035

Chain	Residue
A	ARG931
A	ALA936
A	HOH3614

site_id	FC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 2036

Chain	Residue
A	GLN302
A	LYS311
A	ASN312
A	LYS418
A	HOH3010
A	HOH3136
A	HOH3138

site_id	FC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 2037

Chain	Residue
A	ARG682
A	GLY684

site_id	FC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 2038

Chain	Residue
A	GLN156
A	ASN157
A	LYS216
A	HOH3011

site_id	FC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 2039

Chain	Residue
A	LYS874
A	GLN975
A	VAL976
A	THR977
A	HOH3633
A	HOH3634

site_id	GC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 2040

Chain	Residue
A	LEU182
A	ASP183
A	GLN917
A	HOH3020
A	HOH3023

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