4CS2

Catalytic domain of Pyrrolysyl-tRNA synthetase mutant Y306A, Y384F in its apo form

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0004812	molecular_function	aminoacyl-tRNA ligase activity
A	0005524	molecular_function	ATP binding
A	0043039	biological_process	tRNA aminoacylation

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PEG A 1458

Chain	Residue
A	ASN346
A	HOH2124

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 1459

Chain	Residue
A	TYR242
A	LEU246
A	GLU249
A	LYS431
A	HIS432
A	HOH2029

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 1460

Chain	Residue
A	ARG439
A	ALA440
A	ASN448
A	GLY449
A	HOH2117
A	ASN241

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site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 1461

Chain	Residue
A	PHE289
A	ASP292
A	PHE295
A	GLU340
A	HOH2125

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site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO A 1462

Chain	Residue
A	GLY351
A	SER352
A	GLY353
A	CYS354
A	PRO416
A	HOH2089

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