4CNS
Crystal structure of truncated human CRMP-4
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE PEG C 1489 |
| Chain | Residue |
| C | ILE240 |
| C | HOH2122 |
| D | GLU230 |
| C | SER244 |
| C | LEU263 |
| C | GLN266 |
| C | ALA267 |
| C | LYS270 |
| C | ASN272 |
| C | HOH2071 |
| C | HOH2088 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1490 |
| Chain | Residue |
| A | GLU230 |
| A | ALA233 |
| A | SER259 |
| B | LYS270 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1491 |
| Chain | Residue |
| A | PHE237 |
| A | LYS270 |
| A | HOH2099 |
| A | HOH2106 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 1492 |
| Chain | Residue |
| A | ALA300 |
| A | PHE336 |
| A | LYS341 |
| A | GLY354 |
| A | ASN356 |
| A | ALA429 |
| A | TYR431 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL D 1490 |
| Chain | Residue |
| D | TYR170 |
| D | ARG227 |
| D | HOH2061 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 1493 |
| Chain | Residue |
| A | TYR170 |
| A | ARG227 |
| A | HOH2067 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 1489 |
| Chain | Residue |
| B | TYR170 |
| B | ARG227 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL C 1490 |
| Chain | Residue |
| C | TYR170 |
| C | ILE205 |
| C | ARG227 |
| C | HOH2046 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG B 1490 |
| Chain | Residue |
| B | ASP128 |
| B | GLY464 |
| B | GLY466 |
| B | HOH2037 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG D 1491 |
| Chain | Residue |
| D | ASP128 |
| D | GLY464 |
| D | GLY466 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG C 1491 |
| Chain | Residue |
| C | ASP128 |
| C | GLY464 |
| C | GLY466 |
| site_id | BC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE MG A 1494 |
| Chain | Residue |
| A | ASP128 |
| A | GLY464 |
| A | GLY466 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A 1495 |
| Chain | Residue |
| A | LYS254 |
| A | ILE279 |
| A | THR303 |
| A | HOH2103 |
| A | HOH2119 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q62188","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"17081983","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"24275569","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
