4CG4

Crystal structure of the CHS-B30.2 domains of TRIM20

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE DHL C 1

Chain	Residue
C	CYS639
C	SER675
C	LYS677
C	GLY678
C	ASN679
C	TYR688

---

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE DHL C 2

Chain	Residue
C	ARG717
C	CYS773

---

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE DHL D 3

Chain	Residue
D	SER675
D	LYS677
D	GLY678
D	TYR688
D	CYS639

---

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE DHL E 4

Chain	Residue
E	CYS639
E	SER675
E	LYS677
E	ASN679
E	TYR688

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE DHL F 5

Chain	Residue
F	CYS639
F	SER675
F	LYS677
F	GLY678
F	ASN679
F	TYR688

---

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 1776

Chain	Residue
B	ARG652
C	ARG652

---

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 E 1786

Chain	Residue
D	ARG652
E	ARG652

---

site_id	AC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE SO4 F 1789

Chain	Residue
F	ARG652

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 E 1787

Chain	Residue
E	ARG441
E	SER614
E	ASP615
E	ASP616

---

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 1777

Chain	Residue
B	GLY651
B	ARG652

---

site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 1789

Chain	Residue
C	GLY651
C	ARG652
C	ARG725

---

site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 1789

Chain	Residue
D	GLY651
D	ARG652
D	ARG725

---

site_id	BC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO D 1790

Chain	Residue
D	TRP547
D	THR548

---

site_id	BC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO B 1778

Chain	Residue
B	LYS546
B	TRP547
B	THR548

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	975
Details	Domain: {"description":"B30.2/SPRY","evidences":[{"source":"PROSITE-ProRule","id":"PRU00548","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	972
Details	Region: {"description":"Required for homotrimerization and induction of pyroptosomes","evidences":[{"source":"PubMed","id":"17964261","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	102
Details	Motif: {"description":"Nuclear localization signal","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---