4CCH

Crystal structure of the large fragment of DNA polymerase I from Thermus Aquaticus in an open binary complex with d5SICS as templating nucleotide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001882	molecular_function	nucleoside binding
A	0003676	molecular_function	nucleic acid binding
A	0003677	molecular_function	DNA binding
A	0003887	molecular_function	DNA-directed DNA polymerase activity
A	0006260	biological_process	DNA replication
A	0006261	biological_process	DNA-templated DNA replication
A	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE FMT A 1833

Chain	Residue
A	PRO579
A	ASN580

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE FMT A 1834

Chain	Residue
A	ALA735
A	ARG736
A	VAL737

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site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE FMT A 1835

Chain	Residue
A	TRP428
A	HOH2033

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site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG B 1112

Chain	Residue
B	HOH2010
B	HOH2011
B	HOH2012
B	HOH2013
B	HOH2008
B	HOH2009

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site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE GOL C 1217

Chain	Residue
C	DG213
C	DG214

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site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE FMT A 1836

Chain	Residue
A	ARG313

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Functional Information from PROSITE/UniProt

site_id	PS00447
Number of Residues	20
Details	DNA_POLYMERASE_A DNA polymerase family A signature. RraAKtinFGvlYgmSahrL

Chain	Residue	Details
A	ARG659-LEU678

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