4CBC
Open-form NavMS Sodium Channel Pore (with C-terminal Domain) after thallium soak
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005216 | molecular_function | monoatomic ion channel activity |
| A | 0005227 | molecular_function | calcium-activated cation channel activity |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0016020 | cellular_component | membrane |
| A | 0030317 | biological_process | flagellated sperm motility |
| A | 0036128 | cellular_component | CatSper complex |
| A | 0055085 | biological_process | transmembrane transport |
| B | 0005216 | molecular_function | monoatomic ion channel activity |
| B | 0005227 | molecular_function | calcium-activated cation channel activity |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0016020 | cellular_component | membrane |
| B | 0030317 | biological_process | flagellated sperm motility |
| B | 0036128 | cellular_component | CatSper complex |
| B | 0055085 | biological_process | transmembrane transport |
| C | 0005216 | molecular_function | monoatomic ion channel activity |
| C | 0005227 | molecular_function | calcium-activated cation channel activity |
| C | 0006811 | biological_process | monoatomic ion transport |
| C | 0016020 | cellular_component | membrane |
| C | 0030317 | biological_process | flagellated sperm motility |
| C | 0036128 | cellular_component | CatSper complex |
| C | 0055085 | biological_process | transmembrane transport |
| D | 0005216 | molecular_function | monoatomic ion channel activity |
| D | 0005227 | molecular_function | calcium-activated cation channel activity |
| D | 0006811 | biological_process | monoatomic ion transport |
| D | 0016020 | cellular_component | membrane |
| D | 0030317 | biological_process | flagellated sperm motility |
| D | 0036128 | cellular_component | CatSper complex |
| D | 0055085 | biological_process | transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE 2CV A 1201 |
| Chain | Residue |
| A | PRO193 |
| A | ASN194 |
| A | TRP196 |
| A | HOH2021 |
| B | SER165 |
| B | LYS166 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE 2CV A 1202 |
| Chain | Residue |
| A | TYR153 |
| A | VAL197 |
| A | PHE198 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA A 1301 |
| Chain | Residue |
| A | NA1302 |
| A | NA1302 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA A 1302 |
| Chain | Residue |
| A | NA1301 |
| A | NA1301 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE 2CV B 1201 |
| Chain | Residue |
| A | SER165 |
| A | TYR169 |
| B | PRO193 |
| B | ASN194 |
| B | TRP196 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE 2CV B 1202 |
| Chain | Residue |
| B | ALA145 |
| B | TYR153 |
| B | ALA195 |
| B | VAL197 |
| B | PHE198 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE 2CV C 1201 |
| Chain | Residue |
| C | PRO193 |
| C | ASN194 |
| C | TRP196 |
| C | HOH2022 |
| D | SER165 |
| D | LYS166 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA C 1302 |
| Chain | Residue |
| C | NA1303 |
| C | NA1303 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE NA C 1303 |
| Chain | Residue |
| C | NA1302 |
| C | NA1302 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE 2CV D 1201 |
| Chain | Residue |
| C | SER165 |
| C | LYS166 |
| D | PRO193 |
| D | ASN194 |
| D | TRP196 |
| D | HOH2022 |
| D | HOH2023 |
