4CB6

Structure of Influenza A H5N1 PB2 cap-binding domain with bound cap analogue (compound 11)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0039694	biological_process	viral RNA genome replication
B	0003723	molecular_function	RNA binding
B	0039694	biological_process	viral RNA genome replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE 29R A 1483

Chain	Residue
A	SER321
A	PHE323
A	HIS357
A	GLU361
A	PHE363
A	LYS376
A	PHE404
A	GLN406
A	IOD1486

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 1484

Chain	Residue
A	ARG355
A	MET431

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site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 1485

Chain	Residue
A	ASN456

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 1486

Chain	Residue
A	PHE325
A	29R1483

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site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 1487

Chain	Residue
A	ASN429
A	HIS432

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site_id	AC6
Number of Residues	10
Details	BINDING SITE FOR RESIDUE 29R B 1483

Chain	Residue
B	SER321
B	PHE323
B	SER337
B	HIS357
B	GLU361
B	PHE363
B	LYS376
B	PHE404
B	GLN406
B	IOD1484

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site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD B 1484

Chain	Residue
B	PHE325
B	29R1483

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site_id	AC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 1485

Chain	Residue
B	MET460

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site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD B 1487

Chain	Residue
B	THR378
B	HOH2049

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site_id	BC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 1489

Chain	Residue
B	HOH2045

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