4CB0
Crystal structure of CpxAHDC in complex with ATP (hexagonal form)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000155 | molecular_function | phosphorelay sensor kinase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0016020 | cellular_component | membrane |
| A | 0016310 | biological_process | phosphorylation |
| A | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
| B | 0000155 | molecular_function | phosphorelay sensor kinase activity |
| B | 0007165 | biological_process | signal transduction |
| B | 0016020 | cellular_component | membrane |
| B | 0016310 | biological_process | phosphorylation |
| B | 0016772 | molecular_function | transferase activity, transferring phosphorus-containing groups |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ATP A 501 |
| Chain | Residue |
| A | ASN360 |
| A | THR406 |
| A | ALA409 |
| A | GLY416 |
| A | THR417 |
| A | GLY418 |
| A | LEU419 |
| A | GLY420 |
| A | LEU421 |
| A | TYR364 |
| A | ASP386 |
| A | PRO389 |
| A | GLY390 |
| A | VAL391 |
| A | ILE399 |
| A | TYR404 |
| A | ARG405 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ATP B 501 |
| Chain | Residue |
| A | HIS248 |
| B | ASN360 |
| B | TYR364 |
| B | ASP386 |
| B | PRO389 |
| B | GLY390 |
| B | VAL391 |
| B | ILE399 |
| B | ARG405 |
| B | THR406 |
| B | ALA409 |
| B | THR417 |
| B | GLY418 |
| B | LEU419 |
| B | GLY420 |
| B | LEU421 |
| B | LEU445 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1456 |
| Chain | Residue |
| A | LYS377 |
| B | ARG446 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1457 |
| Chain | Residue |
| A | PRO441 |
| A | ARG446 |
| B | LYS377 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1458 |
| Chain | Residue |
| A | SER271 |
| A | LYS272 |
| B | ARG267 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1459 |
| Chain | Residue |
| A | ARG410 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"24492262","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 32 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24492262","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphohistidine; by autocatalysis","evidences":[{"source":"PROSITE-ProRule","id":"PRU00107","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"24492262","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"9401031","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
