4C9G
Structure of yeast mitochondrial ADP/ATP carrier isoform 2 inhibited by carboxyatractyloside (C2221 crystal form)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005471 | molecular_function | ATP:ADP antiporter activity |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005743 | cellular_component | mitochondrial inner membrane |
| A | 0006839 | biological_process | mitochondrial transport |
| A | 0006915 | biological_process | apoptotic process |
| A | 0009060 | biological_process | aerobic respiration |
| A | 0009061 | biological_process | anaerobic respiration |
| A | 0015297 | molecular_function | antiporter activity |
| A | 0015866 | biological_process | ADP transport |
| A | 0015867 | biological_process | ATP transport |
| A | 0015886 | biological_process | heme transport |
| A | 0016020 | cellular_component | membrane |
| A | 0055085 | biological_process | transmembrane transport |
| A | 0140021 | biological_process | mitochondrial ADP transmembrane transport |
| A | 1901612 | molecular_function | cardiolipin binding |
| A | 1990544 | biological_process | mitochondrial ATP transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 24 |
| Details | Transmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"24474793","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"24474793","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 21 |
| Details | Transmembrane: {"description":"Helical; Name=4","evidences":[{"source":"PubMed","id":"24474793","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=5","evidences":[{"source":"PubMed","id":"24474793","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 20 |
| Details | Transmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"24474793","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 5 |
| Details | Region: {"description":"Important for transport activity","evidences":[{"source":"UniProtKB","id":"P12235","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 5 |
| Details | Motif: {"description":"Nucleotide carrier signature motif","evidences":[{"source":"UniProtKB","id":"P02722","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24474793","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
