4C9G
Structure of yeast mitochondrial ADP/ATP carrier isoform 2 inhibited by carboxyatractyloside (C2221 crystal form)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005471 | molecular_function | ATP:ADP antiporter activity |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005743 | cellular_component | mitochondrial inner membrane |
| A | 0005778 | cellular_component | peroxisomal membrane |
| A | 0006839 | biological_process | mitochondrial transport |
| A | 0006915 | biological_process | apoptotic process |
| A | 0009060 | biological_process | aerobic respiration |
| A | 0009061 | biological_process | anaerobic respiration |
| A | 0015297 | molecular_function | antiporter activity |
| A | 0015866 | biological_process | ADP transport |
| A | 0015867 | biological_process | ATP transport |
| A | 0015886 | biological_process | heme transport |
| A | 0016020 | cellular_component | membrane |
| A | 0042626 | molecular_function | ATPase-coupled transmembrane transporter activity |
| A | 0055085 | biological_process | transmembrane transport |
| A | 0071705 | biological_process | nitrogen compound transport |
| A | 0140021 | biological_process | mitochondrial ADP transmembrane transport |
| A | 1990544 | biological_process | mitochondrial ATP transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 27 |
| Details | TRANSMEM: Helical; Name=1 => ECO:0000269|PubMed:24474793 |
| Chain | Residue | Details |
| A | PHE23-LEU50 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 24 |
| Details | TRANSMEM: Helical; Name=2 => ECO:0000269|PubMed:24474793 |
| Chain | Residue | Details |
| A | THR91-PHE115 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=3 => ECO:0000269|PubMed:24474793 |
| Chain | Residue | Details |
| A | TYR123-LEU143 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 21 |
| Details | TRANSMEM: Helical; Name=4 => ECO:0000269|PubMed:24474793 |
| Chain | Residue | Details |
| A | PHE193-LEU214 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=5 => ECO:0000269|PubMed:24474793 |
| Chain | Residue | Details |
| A | LEU228-LEU248 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 20 |
| Details | TRANSMEM: Helical; Name=6 => ECO:0000269|PubMed:24474793 |
| Chain | Residue | Details |
| A | CYS288-LEU308 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:24474793 |
| Chain | Residue | Details |
| A | ARG96 | |
| A | LYS108 | |
| A | ARG252 |
