4C7D
Structure and activity of the GH20 beta-N-acetylhexosaminidase from Streptomyces coelicolor A3(2)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| A | 0004563 | molecular_function | beta-N-acetylhexosaminidase activity |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0016020 | cellular_component | membrane |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0030203 | biological_process | glycosaminoglycan metabolic process |
| B | 0004553 | molecular_function | hydrolase activity, hydrolyzing O-glycosyl compounds |
| B | 0004563 | molecular_function | beta-N-acetylhexosaminidase activity |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0016020 | cellular_component | membrane |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0030203 | biological_process | glycosaminoglycan metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1495 |
| Chain | Residue |
| A | ASP301 |
| A | TRP332 |
| A | TRP349 |
| A | TYR381 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 1496 |
| Chain | Residue |
| A | GLU432 |
| A | HOH2177 |
| A | ARG150 |
| A | TYR381 |
| A | ASP383 |
| A | LEU394 |
| A | TRP396 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 1497 |
| Chain | Residue |
| A | HIS226 |
| A | LEU227 |
| A | HOH2204 |
| A | HOH2250 |
| A | HOH2289 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1498 |
| Chain | Residue |
| A | GLU80 |
| A | ASN171 |
| A | LYS172 |
| A | ARG294 |
| A | HOH2292 |
| A | HOH2431 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1499 |
| Chain | Residue |
| A | GLU216 |
| A | ALA289 |
| A | LEU290 |
| A | THR291 |
| A | PRO292 |
| A | HOH2286 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1500 |
| Chain | Residue |
| A | GLU217 |
| A | ARG220 |
| A | HOH2241 |
| A | HOH2244 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 1501 |
| Chain | Residue |
| A | ASP156 |
| A | GLU157 |
| A | ARG160 |
| A | HOH2071 |
| A | HOH2187 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 1502 |
| Chain | Residue |
| A | ASN240 |
| A | PRO257 |
| A | LEU258 |
| A | TYR259 |
| A | HOH2267 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 1503 |
| Chain | Residue |
| A | ARG138 |
| A | TYR139 |
| A | VAL422 |
| B | ALA1 |
| B | GLU2 |
| B | HOH2002 |
| B | HOH2005 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 1495 |
| Chain | Residue |
| B | VAL271 |
| B | TYR277 |
| B | ALA313 |
| B | ARG317 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1496 |
| Chain | Residue |
| B | GLU80 |
| B | ALA140 |
| B | LYS172 |
| B | ARG294 |
| B | HOH2464 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1497 |
| Chain | Residue |
| B | ASP352 |
| B | LYS359 |
| B | TYR413 |
| B | PRO415 |
| B | HOH2355 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 1498 |
| Chain | Residue |
| B | HIS226 |
| B | GLU228 |
| B | HOH2217 |
| B | HOH2266 |
| B | HOH2267 |
| B | HOH2465 |
| site_id | BC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 1499 |
| Chain | Residue |
| B | ARG150 |
| B | TYR381 |
| B | ASP383 |
| B | TRP396 |
| B | TRP430 |
| B | GLU432 |
| B | HOH2190 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 1500 |
| Chain | Residue |
| B | ARG220 |
| B | TYR221 |
| B | SER224 |
| B | ARG225 |
| B | HOH2208 |
| B | HOH2466 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 1501 |
| Chain | Residue |
| B | ARG403 |
| B | HOH2447 |
| B | HOH2467 |
| site_id | BC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 1502 |
| Chain | Residue |
| B | PRO13 |
| B | ALA14 |
| B | SER15 |
| B | VAL16 |
| B | HOH2016 |
| B | HOH2023 |
| B | HOH2027 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 1503 |
| Chain | Residue |
| B | ASP156 |
| B | ARG160 |
| B | ASP163 |
| B | TYR221 |
| site_id | CC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 1504 |
| Chain | Residue |
| B | HOH2466 |
| B | SER224 |
| B | HOH2061 |
| B | HOH2268 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1505 |
| Chain | Residue |
| B | ASN240 |
| B | PRO257 |
| B | TYR259 |
| B | HOH2297 |
| B | HOH2470 |
| site_id | CC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO B 1506 |
| Chain | Residue |
| B | ALA303 |
| B | HIS304 |
| site_id | CC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO B 1507 |
| Chain | Residue |
| B | VAL264 |
| B | TRP396 |
