4C6T

Crystal structure of the RPS4 and RRS1 TIR domain heterodimer

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0007165	biological_process	signal transduction
B	0007165	biological_process	signal transduction
C	0007165	biological_process	signal transduction
D	0007165	biological_process	signal transduction

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE MLA B 1179

Chain	Residue
A	ARG140
C	SER130
C	SER132
D	ARG28
D	SER33
D	VAL36
D	THR37
D	LYS40

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MLA D 1179

Chain	Residue
B	ARG28
B	SER33
B	VAL36
B	THR37
B	LYS40
C	ARG140
A	SER130

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	Region: {"description":"Important for interaction with RPS4","evidences":[{"source":"PubMed","id":"24744375","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	161
Details	Domain: {"description":"TIR","evidences":[{"source":"PROSITE-ProRule","id":"PRU00204","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Region: {"description":"Important for interaction with RRS1","evidences":[{"source":"PubMed","id":"24744375","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00204","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"V9M398","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---